dont know weather you got the express news paper this... - NRAS

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dont know weather you got the express news paper this morning

minka profile image
14 Replies

guy in america has solved the ra problem he recons

due to a gene in the joints think it was d

which is a fat deposit and recons he can give antibiotics that would take out this gene and restore normality

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minka profile image
minka
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14 Replies
binlid profile image
binlid

oooh that would be good news hope he does xxxx

sylvi profile image
sylvi

I'll believe it when it happens.xx

artyone profile image
artyone

Sounds amazing bring it on

cathie profile image
cathie

I never believe anything in the express

miss profile image
miss

That would be brill. Can i have it NOW

Ozzy profile image
Ozzy

Me too. I used to go to the gym 3/4 times a week before ra appeared, Oh to be able too again ....... dream on I think is the real answer!

Mumoftwin17 profile image
Mumoftwin17

I agree with Cathie!!!!!...........Sadly.....

Hi Minka,

I have copied and pasted the article (below)

whatever happens, I think it's promising :) thanks for posting this Minka, cheers me up to know about the constant research going on on our behalf, Dr Banda has spent 14 years looking for this gene, so something surely must ring true?

They have discovered that fat cells in the joints trigger the disease, which could pave the way for a powerful new treatment offering hope to millions.

Sufferers could be treated with a simple “gene therapy” drug which blocks the biological process that sparks the agonising condition.

Dr Nirmal Banda of the University of Colorado School of Medicine said: “Our goal would be to stop the disease before it progresses and leads to joint destruction.

“If so, we will be making a major stride toward treating and perhaps even curing rheumatoid arthritis.”

Dr Banda, associate professor of medicine in the university’s Division of Rheumatology, said: “We found that fat in the joints secretes a protein called pro-factor D. That gives rise to another protein, known as factor D, that is linked to arthritis.”

Following the discovery in studies of arthritic mice, Dr Banda is now working on gene therapies to eliminate the protein in localised areas.

He has spent the past 14 years tracking down the causes of rheumatoid arthritis, a chronic auto-immune disease which gradually destroys bones, muscles, joints, cartilage and other connective tissue.

It is sparked when the immune system – which usually fights infection – attacks cells that line the joints.

The disease blights the lives of almost 700,000 people in Britain and is more prevalent among women.

There is currently no cure. Patients suffer severe pain and stiffness in their joints, as well as fatigue and loss of mobility. One in four is registered disabled within three years of diagnosis.

It is estimated that the total cost to the UK economy from the condition is at least £4.7billion a year.

Dr Banda, senior author of the study published in the Journal of Immunology, said: “We are looking at vaccines, drugs or inhibitors to stop the local secretion of pro-factor D.

“Fat is normally present around all organs of the body. What we didn’t know until now was that the fat is secreting this protein which actually triggers arthritis in the joints.”

This research is aiming to understand the inflammatory process, rather than leading to a therapy in the short term

Spokeswoman for Arthritis Research UK

Factor D is part of the so-called “complement system”, a mix of more than 40 proteins which help the body fight off infection.

Removing factor D, rather than the entire complement system, does not damage resistance to infection.

A spokeswoman for Arthritis Research UK, said: “This is very early, basic science in an interesting area of research.

Arthritis Research UK is funding work into the complement system, which has an impact on inflammation in the body.

“Currently no forms of gene therapy are effective in treating rheumatoid arthritis. This research is aiming to understand the inflammatory process, rather than leading to a therapy in the short term.”

Existing treatments for rheumatoid arthritis, called disease-modifying anti-rheumatic drugs or DMARDs, can help slow its progress and minimise joint damage but can have potentially dangerous side-effects.

_andy_ profile image
_andy_

it would be nice to read one of these stories one day , without them saying ..

( It is estimated that the total cost to the UK economy from the condition is at least £4.7billion a year. )

good read john ... thanks for sharing ... lets hope Dr Banda ,, is right in his work ..

minxy1960 profile image
minxy1960

Thanks for posting that, I think there has been a cure for many diseases ,many cancer,s included but its all down to money money money, us humans are not yet worthy of a healthy living , money talks ,and the majority of us lack that. So we suffer , for many they the (medical profession) don't even realise the pain each day ,just to get through the day with no pain like when we where all kids not a care in the world theses where the days ! ! genes have a lot to answer for .

X Angie x

hi Minka, wouldn't this be amazing if this comes into effect it would bring relief to so many of us . Thank you for enlightening us . I will remember to mention this to my consultant as he is a professor and is part of the research team at the birmingham University into RA . It may be interesting to learn if he has also seen this. will keep you posted not due to see him till July but its worth asking. hugs Lena xxxx :)

jeanabelle profile image
jeanabelle

Well, we can dream, can't we?

Kathyfitz12 profile image
Kathyfitz12

Just think - if this country stopped throwing aid at ungrateful countries what it could do with the money?

How many time have we been told we are providing clean water in Africa - yet still most of Africa doesn't have it....so where did the money go.?

If it had been spent on medical research maybe we wouldn't be reading/writing this today?

minka profile image
minka

trouble is with these things they are not available till yeaqrs ahead which is no good to people now

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