Red ends on fingers above nails

[Cmelak]

ET Jak2 on Hydrea 500mg and aspirin. I am developing red areas around my fingernails and pain in some knuckles. Any advice?

[MissLesley13]

Hi. I am also on hydrea and asprin. I got really red marks and itching and I had to take an antihistamine. The hospital recommended piriton . I get a lot of bone pain and I have noticed it a lot more lately. I get a lot in feet , hands , feet and hips. I hope this helps

[sbs_patient]

I was on HU for about five years and had to quit because of serious skin reactions (fingers, nails, backs of hands). This is a well known side effect.

[Cmelak in reply to sbs_patient]

Also, my hemoglobin is low so maybe it has something to do with circulation. I will talk to doctor in my next appointment. I am just 9 weeks in the treatment and not sure that hydroxyurea is right medication since my platelets are around 500 but becoming anemic. Not sure how it works yet.

[sbs_patient]

My MPN journey is approaching its 10th anniversary; I was diagnosed with PV back in 2015, treated first with phlebotomy alone, then with HU, and finally with Jakafi since August 2022. My blood numbers have been stable since I started Jakafi. I should probably also mention that I am a few weeks away from my 81st birthday.

[hunter5582]

This sounds like a possible HU side effect. Best to let your MPN care team know and have your uric acid levels checked as HU can cause renal impairment which can affect joints.

[Blue-IvyBoo]

I experienced something similar..what worked for ME was a high quality live pre and pro biotic...taking Hu is soo hard on your stomach and body in general.. I doubled up and its been a game changer..no redness itchiness or burning sensation in my feet and fingers since starting Hu in January..please consult before trying.!