I am sixty-seven. I started having migraines when I was five. I have had every procedure you can think of including a nerve stimulator, nerve blocks, cranial nerve cutting, Botox injections and about forty different prophylactic drugs, all under the supervision of the neurology departments at Queen Square and Addenbrooke's. The consultants I have been treated by have been thorough and well-meaning despite being overwhelmed by the number of chronic migraine cases they deal with daily. Over the years I have met dozens of people with chronic migraine desperate for help. Most of us suffer from chronic rebound headaches caused by the very drugs we take to stave off the pain. Triptans are the best and the worst of drugs: the only drugs which effectively abort an attack but highly addictive: cold turkey is one of the worst experiences anyone can go through. If you take triptans you will need to go through cold turkey over and over again as you struggle to become drug free.
Once you have eliminated all the trigger factors which make things worse: alcohol, junk food, wheat, dairy products, anything with caffeine in it... you're left with those triggers which you cannot control: low pressure, strong smells, pollution, noise and bright lights in public buildings. I'm sure everyone has their own list of triggers.
The idea of a prophylactic drug is wonderful but the reality is that every one I've spent months and months, even years trying has had such serious side effects that the relief from pain, which was real, was less impressive than losing my mental capacity, creativity, intellect. It can be wonderful feeling no pain at all for the first time in one's life but the cost is very high if it means giving up work and ceasing to function as the person you were before you took Epilim or Topirimate (which also causes kidney stones) or any of the many other calcium channel blocking drugs. Pain or Brain Loss? You have to choose.
I'm pretty sure that migraine will be cured only when someone identifies the faulty gene which causes it and finds some way of zapping that. In the meantime, I wish doctors would be honest with patients and help them manage chronic pain rather than suggest the condition can be cured. It is not a life-threatening condition, it just means life is very painful, more limited than it would be without the attacks.