I've been treated for depression for the last 20 years, the lady 8 years by a psychiatrist. I've been on just about every medication and combination of medications there are. it works for a period of time, then my symptoms get worse. I am under an enormous amount of stress that is just part of my life, can't be reduced. I am 60 years old and was once a vibrant actuve, outgoing person. I don't even want to leave the house now.