My daughter has been unwell for nigh on 2 years with fatigue, rashes, joint pain, sore throat, depression and as I have Lupus I am becoming more of the opinion that so has she. She was at the Doc (again) this week with a sore throat (again) and he diagnosed tonsilitis (again). He gave her Doxicycline and she had a major allergic reaction. When we looked into it more this antibiotic is contra-indicated in SLE. I am allergic to Septrin. She is in what I would now class as a flare. Anyone else this is virtually diagnostic? GP had to treat the allergy with steroids so I demanded a Rheumy referal for her which he did begrudgingly.