Samuel Taylor Coleridge had a number of chronic illnesses which he managed with all sorts of medications, including, at last, copious amounts of laudanum. Here's his poem of 1790, "Pain: composed in sickness"
Once could the Morn’s first beams, the healthful breeze,
All Nature charm, and gay was every hour: —
But ah! not Music’s self, nor fragrant bower
Can glad the trembling sense of wan Disease.
Now that the frequent pangs my frame assail,
Now that my sleepless eyes are sunk and dim,
And seas of Pain seem waving through each limb —
Ah what can all Life’s gilded scenes avail?
I view the crowd, whom Youth and Health inspire,
Hear the loud laugh, and catch the sportive lay,
Then sigh and think — I too could laugh and play
And gaily sport it on the Muse’s lyre,
Ere Tyrant Pain had chas’d away delight,
Ere the wild pulse throbb’d anguish thro’ the night!
Help create a national register for people with rare rheumatic diseases
Out of spoons by end of day
\"day without laughter is a day wasted\"
Ok, just having a bad day 
First day back at uni!
