It's driving me crazy!!!!! Started fluoxetine 2 weeks ago, also antibiotics started at same time for an abscess. Finished antibiotics after 7 days, 3 days later my bladder irritation started, literally needing a wee every ten minutes, and feel need for wee straight away. Thought it may be thrush ( after antibiotics ), so took a tablet for thrush on Sunday and had sachets for cystitis. It's now Tuesday and no improvement. Saw GP this morning, he did dip test, no sign of infection. Could this be the fluoxetine or part of lupus?