I am getting to the end of my tether with the entire medical profession I'm sorry to say. I am 69 and todate I'm so complicated not one doctor has actually made the correct diagnosis. My mother gave me Psoriasis PsA Scoiliosis and she had Colitis. My father had flat feet and gave me PCOS and he had Crohn's. I was a wobbly sick kid who lost over 4 years of state education but wanted to be a doctor. Unfortunately that didn't happen but I did make it to Cambridge in the 60s. Then I worked in medical underwriting. We had 5.5 children the .5 was killed by a GP OD, then our adopted son, then Robin who was a cot death, then came babies 3&4 and finally on the pill 8 years later came 5! I have had far far too much progestogen for a hypermobile person. If I ever hear no again I think I will scream! It's been yes you have Sjögren's no you don't. Get the picture? Finally diagnosed with Lupus by a skin consultant then upped on MTX until I was injecting 25mg. Then I was told I was a waste of clinic time. I nearly died. Then back on MTX injections finally in order to get to the bottom of this last year I went to UCH to be told of course you have Lupus. But no consultant says I have only Sjögren's no POTS and certainly not Ehlers Danlos. Phoned secretary oh my consultant is an EDS expert! Well that's good, my goodness what a quick learner as I only gave the books the previous week. So why I ask am I going for a genetic test for a disease for which there are no drugs, I was told? Of course there are drugs but I'm getting so cross I'm tempted to never see a doctor again. With private health and ignorant Consultants I'm now a cripple. Sorry folks for the rant but I'm really end of tetherish with numerous homogenous ANAs what else have I got?!