Deep down I know the answer to this but just after a bit of reassurance and to see how many of you feel the same. One of the first signs of a flare for me is anxiety and depression. Can't cope with the simplest problem and my head feels on a different planet, feel so sick with anxiety I can't eat and feel the world is against me. It does lift eventually when the flare goes but whilst I'm feeling like it I feel like I'm going mad! Always feel like I need to take something as it gets so bad but then it will ease again so not sure if any antidepressants or anything would help. Does anyone else feel like this?