ASPIRIN RISK OF BLEED IN NEWS

[dexters]

Hi all have you seen this in the news on line , Study links aspirin to increased bleeding.

Anyone like me positive no known clots will have to twist docs arm to recommend aspirin .

Regards Dexters

[dexters]

Hi StickyBloodMentor

You are so right , but some docs dont understand sludgeblood.

i educated my gp by giving him a copy of The Patient Patient (he has a sense of humour) and added a link to G.H.I.C.

Regards Dexters

[Tucson]

I was prescribed Aspirin alongside Warfarin until August last year when I had a massive bleed in my pelvis and nearly died so sludge blood won't necessarily protect you from a bleed. I was led to believe it would and had that bleed been elsewhere in my body I'd be dead now. So exercise caution.

[dexters in reply to Tucson]

Hi Tucson

That must have been terrifying for you ,thank you for your advice. What part of the world are you.

Regards Dexters

[Tucson in reply to dexters]

I'm in London.

[Tucson]

Yes I said I was prescribed both by st Thomas's after having a 3rd stroke on Warfarin alone they added the Aspirin and my Inr was kept within range and I was testing frequently and had to keep my Inr above 4 as it was 4 when I had the stroke. I was walking a tightrope with keeping my Inr above 4 and below 4.5 but I was managing as my Inr was very stable. I'm not scaremongering just saying what could happen no matter how careful you are.

[HollyHeski Administrator in reply to Tucson]

I'm on aspirin, clopidogrel and clexane. I never reduce my dose but when I have a flare I will increase dose of clexane. This combination, I have been on fir many years with fortunately no further clots. Don't even think of bleeds as this just makes my blood normal.

I think the latest article is for people taking aspirin as a precaution against strokes and heart attacks but with no other medical condition.

[Tucson in reply to HollyHeski]

I'm currently on clexane and so far so good but you never know until something happens. I don't have flares. The thing is we're all different and what works for one doesn't work for others. I never worried about bleeds until I had one and then there was no point worrying. I always thought my blood was normal, I didn't bruise easily or bleed easily and certainly never thought my blood was too thin. When they take blood I never needed a plaster because I didn't bleed. So although my Inr was stable and didn't wander it was no safeguard against bleeding. I felt safe with regular testing and never worrying about my Inr because it was so stable compared to others but ultimately that meant nothing.

[MaryF Administrator]

I am on two a day and fine with that, my blood behaves far better being on it, but I do always make sure I have a full stomach before taking any Aspirin. MaryF

[dexters in reply to MaryF]

Hi MaryF

My nan allways said aspirin on a full stomach, if you had a cold she would try to get me to drink sherry and a raw egg YUCK

Regards Dexters

[MaryF Administrator in reply to dexters]

Ughrrr, no thanks. MaryF x

[Tofino5]

I’m on a low dose aspirin a day, plus apixaban. Prior to that I was on a low dose aspirin a day, plus warfarin.

MaryF I take the aspirin before bed, so, empty stomach. Maybe I should rethink this timing.

[dexters in reply to Tofino5]

Hi Tofino5

Same answer as to MaryF

Regards Dexters

[Tofino5 in reply to dexters]

Yes, I think so!

[Jumper99]

Was the report about full strength aspirin? We only take low dose aspirin normally. There is a risk for us of bleeding on any of our anticoagulation I think. It’s a balancing act between clotting and bleeding in setting our anticoagulation levels. Clopidogrel is very similar to aspirin but is said to be more gentle on the stomach.

[dexters in reply to Jumper99]

Hi Jumper99

It was about low dose taken as a precaution against stroke sand heart attack , not us sludge bloods ,but convincing the docs is another thing.

Regards Dexters

[KayHimm]

I think it would definitely be worth asking your doctors if an aspirin trial is worthwhile. I felt better when I was put on aspirin for clot prevention years ago. It could not have been the placebo effect because I had no idea it could help with neurological issues. They are now experimenting with an increase in the dose to see if I improve even more. Many people are on daily low dose aspirin because the benefit outweighs the risk of a bleed. I think medication that blocks stomach acid helps prevent GI bleeds, but not sure. Good luck and hope you feel better soon.

[dexters in reply to KayHimm]

HI KayHim

I did twist docs arm to trial aspirin , how long did it take for your neuro symptoms to improve im still foggy and muddled (my wife has to check my typing sometimes it is aspish as she says) On a full stomach and anti acid tabs all help. Thanks for the kind thoughts,

Regards Dexters

[KayHimm in reply to dexters]

What I remember is that after about six months on the low dose aspirin, I realized my neurological symptoms had improved. I wish I could be more specific, but it was at least fifteen years ago, so my account of the events is not reliable. It looks like PPIs do help prevent GI bleeds — but only upper GI tract. That is great that your doctor is willing to try the aspirin. I am guessing, but I would think you could start to notice improvement as soon as the anti-platelet function begins. I think it would take about ten days to affect all platelets. That is why they limit aspirin up to ten days before certain procedures. I do remember having worsening of symptoms when I was off aspirin for about two weeks before and after a procedure. Rooting for you to get some improvement!

[robertbob]

Hi

This article looks pretty thorough in terms of setting out bleeding risks with different combinations of anti-clotting drugs. Although tbh I struggled to understand the figures.

ncbi.nlm.nih.gov/pmc/articl...

cheers

R

[dexters in reply to robertbob]

Hi robertbob

Many thanks, all of the studies are about non sludge bloods no one seems to have done a survey on specifically sludge bloods.

Regards Dexters

[robertbob in reply to dexters]

Hi

The one I posted below might be relevant in that it indicates no excess risk for general population and Im guesing that would also apply to those with APS but I dont know.

[robertbob]

If wondering about aspirin on its own, this might be a useful article.

jwatch.org/na45706/2017/12/...

extract below

Does Low-Dose Aspirin Increase Risk for Intracranial Bleeding?

Allan S. Brett, MD reviewing Cea Soriano L et al. Neurology 2017 Nov 28

A population-based study suggested no excess risk.

During median follow-up of 5.4 years, 1611 cases of intracranial bleeding occurred (46% intracerebral hemorrhage, 30% subdural hematoma, and 24% subarachnoid hemorrhage). In analyses adjusted for various demographic and clinical factors, current use of low-dose aspirin was not associated with excess risk for intracranial bleeding overall (rate ratio, 0.98) or for intracerebral hemorrhage (RR, 0.98), subdural hematoma (RR, 1.23; 95% confidence interval, 0.95−1.59), or subarachnoid hemorrhage (RR, 0.77; 95% CI, 0.58−1.01).

COMMENT

This study, derived from a population-based database, provides reasonable reassurance that low-dose aspirin (i.e., 75−300 mg daily) does not confer excess risk for intracranial bleeding

[dexters in reply to robertbob]

Cheers, what part of the country are you im in south wales

[robertbob in reply to dexters]

yvw. South Wales too. South Westish I guess. In Swansea. I left London when got ill/ divorced etc and ended up in Swansea via Carmarthenshire (which seems to have the worst health services in teh UK but maybe I was just unlucky).

Hope things going OK for you atm. Let me know please if find any support groups. I was being treated for APS but there seems a lack of certianty as to whether or not its what Ive got. Ive certainly got a good collection of brain lesions, livedo, swollen hands, tinnitus, crazy visual symtpoms etc bleeding etc. But who knows.

Cheers

R

[dexters in reply to robertbob]

Hi robertbob

Im near Bridgend as far as nhs goes bit ignorant of aps west of bridgend have a read of my aps journey posted 22 days ago, i dont know of any groups not many diagnosed with aps in south wales. There is a recommended rhumy in the royal glam. talbot green dr ceril rhys-dillon. Who are you seeing at the moment , i am waiting for a haemo appointment in swansea. If you want a giggle have a read of the patient patient an ode to aps. i posted 11 days ago. You need to see someone who understands aps. take care.

Regards Dexters

[robertbob in reply to dexters]

Thanks Dexters and apologies for delay replying. Im not on here much atm.

I did earlier look at your APS journey post and it looks like it must have been incredibly frustrating but unfortunately not all that atypical for folk with undiagnosed autoimmune disorders. I will look into the Dr you mention for sure. I think Hwyel Dda was not the best catchement area in which to get ill and Im hoping that now under different health board that things might improve.

I saw a consultant at the Spire and then got referred to London Bridge. Both consultants seemed good. Im happy to PM you the names if would be helpful. I had been told that it would take a year to see someone on the NHS, which must be against NICE guidelines but I didnt really feel up to a fight about it.

You are probably right about support groups. maybe need a support group in thse parts which covers a number of autoimmune conditions so as to get enough people?

anyways, thanks again and look after yourself.

cheers

R

[dexters in reply to robertbob]

Hi robertbob

Nice to here from you please pm me who you saw at spire, if i here of any support groups i will let you know. Take care

Regards Dexters