Medical history practically nonexistent prior to 65. Dx’d hypo (2015) of blood test and started mylan levo. First reaction in eyes and a sort of full body cascade continued for 8+ months. Stopped meds - reactions stopped. About 2 weeks after starting mylan levo I had what I described as a quasi seizure - no stroke symptoms. Started synthroid and more reactions. After 5 months started tirosint and after 1.5 months all reactions stopped and have not resurfaced. I’m asymptomatic for hypo/ hashi (dx’d during mylan reactions) and thyroid meds were the only thing I was taking until 11/2018 when statin was started. Switched Medicare plans for better docs knowing I would not be able to get tirosint but could compound t4 in an olive oil suspension. 4/2017 did efudex for a couple of ak’s on nose and follow up was done by new plan docs. I haven’t healed like most so she ordered a couple of lab tests. All were negative except DRVVT which is positive and over range - a bit unusual at my age! Bc of my reactions to the thyroid meds and having no symptoms to chase for labs, I opted to do 23/me as I felt it would provide better insight 3/2017I was not disappointed as I am now continually referring to it for meds and other things. I’m Caucasian and I’m a sickle cell carrier as is my daughter. Genetically, I lack the enzyme for processing warfarin. I was put on low dose aspirin (11/2015) for sed rate but started bruising to the point that my thighs looked like someone had taken a baseball bat to them. I stopped and the bruising stopped. So questions:
Alternatives to aspirin?
Cardiologist wants me on a Mediterranean diet, pcp wants to avoid gluten, soy, sugar, corn. No gut problems so I eat organic but never liked soy and I eat a lot of salads. Any thoughts here?
Does having sickle cell trait influence having APS?
My understanding is that APS is related to factor x in clotting. Is this correct?
Can APS be triggered by my thyroid med reactions ( I have one upload that says I’m an APS carrier - described at APS trait)?
Should I request a hematologist, rheumatologist or an immunologist?
I’m an outlier and totally asymptomatic with slightly elevated (just over/under range but with statin cholesterol is now under range but profile follows an APS profile (research). What might improve this?
TIA