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MikeS1 profile image
14 Replies

Hi, after a couple of years of going to the doctors and rheumatology consultants complaining of muscle pain and fatigue They have confirm my suspicions that it is probable fibro. I have loads of questions and welcome the support, but firstly a bit of advice regarding medication would be appreciated - along with various vitamins I have been talking Meloxicam for some time now, initially every few days, but now daily. The consultant has advised I try Amitriptyline and just wanted to know if this is standard procedure and if there is any significant benefits and side effects I should be aware of. Also can I take both at the same time. Doe’s this time of year with the damp weather make anybody else feel worse!

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MikeS1
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14 Replies
Volatileval profile image
Volatileval

Hi Mike, I tried using Amitriptyline a while ago, but stopped them as one of the side effect was making me dozy during the day and I had a very dry mouth The was uncomfortable. I have some left and I take one now and again as it gives me a good nights sleep. But everyone is different and my advice is to try whatever your dr suggests until you find what suits u best. In my case I’m on Tramadol and naproxen which keeps on top of pain. Sometimes I wonder if I really need them so stop taking them - soon reminded why I take them! Lol

MikeS1 profile image
MikeS1 in reply to Volatileval

Thanks Volatileval, I read about these side effects but if it does work for menthen maybe it’s worth it.

Waddlewaddle profile image
Waddlewaddle

They recommend amitriptyline is taken at night due to the drowsiness side effect

MikeS1 profile image
MikeS1 in reply to Waddlewaddle

Ok thanks Waddlewaddle, also sounds like it will help me sleep better 😀

Waddlewaddle profile image
Waddlewaddle in reply to MikeS1

I took it during the day and felt really out of it so I took just before bed and much better as I slept through side effects!

Chance15 profile image
Chance15 in reply to MikeS1

Hi mike I’ve been taking Amitriptyline 150 mg I take them around 8pm they work for me.

Waddlewaddle profile image
Waddlewaddle in reply to Chance15

Wow 150mg that’s high! I would sleep for ten years on that dose

RayB profile image
RayB

Mike,

Meloxicam is a non steroidal anti-inflamatory,,,, it works by enzyme inhibition, the enzymes that are needed for the body to create inflamation are not produced,,, theirfore less inflamation less pain. Sadly the enzymes that are blocked are used for other things in the body at the same time, so Cox enzyme supression is perhaps not a great idea longterm. Many however use them for very long times without complaint.

Amitriptyline works very differantly,,, exactly how it works, lies in the land of theory and is not proven. Basicly it is thought that with it's use the pain signals somewhere between your brain and the peripheral nerves, the pain signal becomes calmed, or is translated by the brain as less urgent. (all pain is created by the brain)

Amitriptyline can and does work very well. A larger dose will probably be no better than A lower dose,,, so more is not necessaraly more effective,,, many find 10mg enough.

Now,,,, if you have alot of inflamation,,,, what is causing that inflamation.

Your Dr will not be intrested so forget about his help.

The number one with inflamation is diet and to my mind something everyone today with or without fibro needs to adress and sooner rather than later.

It is not something you just instantly do it takes commitment, much reading and changing habbits of a lifetime.

Best Wishes, Ray

MikeS1 profile image
MikeS1 in reply to RayB

Thanks Ray for the clarification. I have started to look at my diet and trying to identify what are the triggers as there are some foods which seem to make my symptoms worse. Mike

Grumpy777 profile image
Grumpy777

Hi Mike, I take amitriptyline and find it helps quite a bit for the nerve pain I get...

MikeS1 profile image
MikeS1 in reply to Grumpy777

Thanks Grumpy777, will give it a go.

Themanwithnoname profile image
Themanwithnoname

Can say Amitriptyline has been good for me. Last week see GP to try something new so come off Amitriptyline for Gabapentin. Found Gabapentin is not for me and how i realised how much Amitriptyline helps me.

MikeS1 profile image
MikeS1 in reply to Themanwithnoname

Thanks tw25, think I’m going to give it a try

bigalan profile image
bigalan

Hi Mike, The weather has a big impact on my pain, much worse in damp cool weather, keep wrapped up, Celafen cream helps me a lot.

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