Severe endometriosis undergoing IVF. ... - Fertility Network UK

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Severe endometriosis undergoing IVF. 300ui of meriofert for stimulation. Will this high dose cause greater pain. Many thanks in advance.

HopefulBee profile image
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37 year old woman. Severe stage 4 endometriosis. Unable to conceive. Surgery May 2024 revealed bilateral endometrioma 9cm and 10cm inside ovaries plastered to back of pelvic wall and attached to bowel. Left fallopian tube wrapped round and stuck to left endometrioma and left endometrioma receiving blood supply from omentum ( fatty layer protecting abdominal organs). Tubal dye test revealed both fallopian tubes blocked and left fallopian tube damaged.

Deepset bowel involvement.

Surgery ablation. Informed further Ssurgery needed by specialist centre after family complete.

AMH level 8.8, all other hormone levels normal. Low immunity. Iron deficient on oral iron.

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Endofitall profile image
Endofitall

I am sorry to hear this. I don’t think the dose specifically is a problem. They use the dose based on your AMH to try and get good response from the ovaries. The number of follicles that respond will produce oestrogen and this is what will usually have the potential to flare the endometriosis. I did find by middle to end of stims my endo was exacerbated. And the more IVF cycles I’ve done the worse it got because of repeated stims. I hope you get your BFP and baby soon and respond quickly. Best of luck.

Behind_Hazel_Eyes profile image
Behind_Hazel_Eyes

Hi I have stage 4 and just about to turn 37! AMH 6.6. been trying to conceive for 7 years. I have done 1 cycle. I was on a high dose for stimulation. I didn't flare. But I was also on an anti-inflammatory diet. I was slow to respond and needed a few more days of the drugs to get my follicles to respond. Unfortunately I only got 2 eggs becuase they couldn't access both ovaries because of the endo. Both eggs were poor quality. They didn't last 24 hours. I have a lot of endo round my ovaries (kissing ovaries and 2 cysts), never had any ablated or excised. Going for excision surgery next week. Like you my tubes are not great, one is also getting removed. Endo is such an awful disease! Wishing you luck!

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