2nd miscarriage/progesterone

[Kt8e21]

Sorry for the long post…

Yesterday I had a miscarriage after an IVF fresh transfer. (They said it was a top graded embryo, I used donor sperm). When I went to the EPU they confirmed that there was no pregnancy sac.. which I was expecting with the amount of blood etc.

I was 11+6.. I had a scan at 7+2 and the baby measured 6+6. This was the last scan I had.. the clinic told me to stop progesterone supplements at 8 weeks even though I asked if I needed to be on them longer due to a previous chemical miscarriage after IUI procedure in May 22. (I was not on progesterone with this pregnancy).

I’m wondering if the embryo stopped developing a few weeks ago since I stopped taking the progesterone and then the miscarriage process has started naturally? (Is this classed as a missed miscarriage and may have been picked up if my 12 week scan was sooner.. it wasn’t booked until 13+2)

Anyway the point of my post.. I’ll be booked in for my follow up appointment at my IVF clinic soon as I’ve still luckily got 5 frozen embryos to use via FET.. should I be asking for anything extra if I get a BFP?

Maybe progesterone longer that 8 weeks? Seems my pregnancy lasted longer than my first and could this be the reason?

Is there anything else I need to be asking my Dr for at the review meeting?

Thank you for reading.

[DianeArnold Partner Nurse Fertility Network UK]

Hi Kt8e/ I am so sorry to hear of the tragic loss of your little one, and hope you have plenty of support just now. I am hoping that as you lost this little one, perhaps they will monitor your progesterone levels to ensure you are getting enough. I must admit that I used to prefer scans being done at 13/40wks as you would be certain of seeing everything required for the nuchal scan too. I wish you every good luck with your next embryo transfer, and let's hope this will be your year. Diane

[Kt8e21 in reply to DianeArnold]

Thank you. I will mention testing progesterone when I have the meeting and see if this is something they can do.

[Emlou87 in reply to Kt8e21]

my clinic agreed to leave me on progesterone until 15weeks xx

[Kt8e21 in reply to Emlou87]

Thank you I’ll definitely question if I can stay on them longer.

[LouCollier]

I'm so sorry for your loss. there are no words.

I had three MC and on my last cycle I had been tested for NK cells (which were high) so I was on meds for that, progestrone injections (previously had pesseries) and blood thinners. took all until 12 weeks

[Kt8e21 in reply to LouCollier]

Thank you. How do they test for Nk cells?

[LouCollier in reply to Kt8e21]

I went to Coventry as part of Tommy trust charity. It cost approx £500 for the biopsy. from the research I did I wanted the biopsy of the area rather than bloods and there aren't many places that do that x

[Lolalules]

so sorry for your loss, it truly is so heartbreaking and i hope you are managing ok.

If it helps, I’m recurrent loss and had been referred to the recurrent loss clinic in London. Even though my progesterone levels were fine pre-FET and clinic let me choose to be on them or not (until 12 weeks), the recurrent loss clinic advised staying on them until 16 weeks. I’m now 22 weeks - could be related or not! Either way, I think medical advice for anyone with multiple loss is to be on progesterone due to recent studies. Hope this helps xx

[Kt8e21 in reply to Lolalules]

Thank you.. you think that all clinics would give same recommendations as the recurrent clinic? But maybe cos I only had 1 previous they wouldn’t suggest it? I’m definitely going to bring it up on my review meeting.

[Lolalules in reply to Kt8e21]

yah i think it’s industry advice now, it’s why clinics will let you do progesterone on natural FET if you’re concerned