I’m 36 and my partner is 40. We’ve had 2 rounds of IVF this year, the first didn’t work, the 2nd did but we miscarriage at 6 weeks. I then fell pregnant naturally straight after but miscarried again at around 5 weeks…
Can anyone recommend any supplements we should be taking?
We have ‘unexplained’ infertility.
Hi there, I’ve just seen my doctor for the same reason and she recommended that I take aspirin 75mg per day whilst trying to conceive/undergoing treatment. It’s best to check with your doctor though but it seems to be the advice healthcare professionals give women who go through repeated miscarriages.In terms of supplements Impryl is good for men and women should take folic acid, a multivitamin and I also take Coq10 x
Thankyou for the info! I’ve got a referral to see the recurrent miscarriage clinic but not until December 🫣I might hold off on the aspirin until then only because it gives me bad indigestion, but i think I’ll get him on the Impryl and myself on Coq10 x
Sounds sensible! I’m about to try the aspirin so will see if my body agrees with it. I also just bought a book called “is your body baby friendly?” which came highly recommended by people who have gone through similar experiences. Will let you know if it’s any good (assuming you haven’t read it yet!). Best of luck xx
Oh no I haven’t heard of it! Thank you yes please let me know 🙏 xx
Hope all goes well with your appointment in December- good idea to hold off on the aspirin till seen at clinic . Make sure having a good healthy varied diet - plenty of fresh veg and the green leafy ones as well. C heck Vit D and E are in your multi vit .Thinking of you
Janet
Thankyou Janet ❤️ I feel like I couldn’t eat much healthier 😬 but I am gluten free (because I have Hashimotos) and so I hope I’m not missing out on some nutrients…I’ll check my multi Vit for E thankyou x
Has anyone mentioned to you that your losses could be immune related at all? (I only ask because you mentioned your Hashimoto’s) I STRONGLY recommend the book suggested above x
Thankyou Kimbob82 yeah I have read about it could be immune related… my GP is testing next week for other autoimmune’s and I’m on the waiting list for the recurrent miscarriage clinic so hopefully they will too. My endo said my thyroid antibodies are really high so I’m guessing it is related but my IVF clinic don’t do any immune testing which is annoying. Thankyou for the recommendation I’ll buy it! Xx
Can I also suggest having a look at Dr Norbert Gleichers videos on YouTube… he is a well known reproductive immunologist from Centre for Human Reproduction in NYC. He specifically talks about the immune system and how auto immune disorders (and even sun clinical auto immunity) affects implantation. They are only short videos and I learnt so much. Good luck x
Thank you I will check it out! It seems a lot of people don’t believe in the immune system being the problem… my clinic doesn’t recognise it. Are steroids te solution? X
It’s madness that they don’t acknowledge it! I’ve done so much research on it and in my opinion it’s verging on medical negligence if they ignore immune related infertility. Anyway, there’s a few different treatments… Dr Gleicher talks about them. Yes steroids, Intralipids, IVIG, low dose naltrexone, clexane, hydroxycloriquine and so the list goes on… But it is treatable. So if you’re creating embryos and you get the right protocol, you’re on the right track…
I had 7 transfers, all BFN because my clinic wasn’t willing to acknowledge that it was my immune system, they kept blaming it on the embryos. So frustrating…
Yeah we managed to freeze some 5 day blasts last time so they’re just not staying. Oh no what did you do? Have you had any success? What immune issues do you have?
I’ve had three chemicals (potentially 4, I just had my hcg today at 10days past 5 day transfer and it’s only 59 so who knows) The first 7 transfers were all bfn, no implantation (without any immune protocol) and I’ve now had another 7 (4 have implanted) and that’s been on an immune protocol. I have lots of different things going on… you’re welcome to message me privately 
I haven’t had success yet but I feel like I’m close, I’m not giving up yet!
I’ll pm you x
Sorry to hear ... check out fertylisis for immune testing . Def recommend. Also have you been checked for endometriosis ? A laparoscopy and hysteroscopy would be really beneficial too. I have had alot of recurrent MC still haven't managed to sort out the immunes. My last baby was tested and was genetically normal so we know 100% it's my immunes at play. I also had silent endo removed and have tried numerous medications. I am getting closer but struggle to reach the 12 week mark. IVIG has been recommended but it's very expensive. However we are not giving up .. we know we will get there eventually. Stay strong on this journey
I haven’t been checked for endo yet, we are NHS patients, hopefully the recurrent miscarriage clinic will so that for us. What immune issues do you have? Have you had the sperm DNA defragmentation test? It’s very difficult to stay strong when it feels like an unsolvable puzzle 😭
I’m so sorry for your losses. Have the doctors suggested supplementing progestrogen? This can really help with early miscarriages and they should be investigating for you since it’s happened twice
I took cyclogest for my IVF rounds, the first I bled before the test day and the second where I had my BFP I spotted before miscarrying. I’ve been asking for Lubion but because we are NHS funded they won’t give it to me. They checked my levels on the day before my FET and said they were sound 60 which was normal but I wonder if they could be higher…
hi MrsTurnertobe, I’m just writing to say I’m also NHS IVF funded and got Lubion. Confirmed Endo in May this year after a MC in Jan and did long protocol for this FET and got positive test but had some heavy bleeding at 6weeks so am waiting to see where that ends but have a good idea 😞
Good to hear about the MC clinic and thread on immunity.. lots to research.
I won’t be funded moving forward but feel like we are close now after the long protocol ..just need to figure it out a bit more. 🤞🏻✨
I’m sorry to hear and hope that it’s nothing to worry about ❤️ Are you going to the EPU for an early scan?
Why won’t you be funded anymore? And will you continue privately? I heard through girls who were at my clinic (the Agora) that there is a really good place in Athens.
I just had a rough night and there is no doubt that we are having MC now…was wishful thinking it was just some heavy bleeding. I phoned the hosp and they said to come to the EPU next week and they will check to see if everything has passed and if not then will take steps for that. Staying on all meds until then.
I was funded for one round of IVF with CCG as I was 40 starting which gave us two rounds of FET, we got 3x 5DFE and transferred two in December and had MC at 9weeks and then went ahead in March for next transfer but had to cancel as something was seen in US..thought I would have to have salpingectomy but then woke up from procedure to find out I was diagnosed with Endometriosis..! So went on long protocol from June for 40+days preparing for our next FET in August which gave a BFP but is now ending in MC.. 😞
I like the consultant and was very happy with how they adjusted everything with the Endo diagnosis-feel they know what they’re doing and from my research I don’t think the price difference of UK vs abroad is that much considering flights&accomodation so I might do another round here.
However if you have any details on this place in Athens then I am open to considering it. Options are good. I heard of a “friend of a friend” who did some test in Athens clinic who diagnosed an infection/inflammation and she was put on some antibiotics and got pregnant ..I must research this again considering my Endo diagnosis and I’m also gluten intolerant so there is certainly something here with inflammation etc that I need to manage.
I have been taking Wild Nutrition brand of supplements which I give a lot of credit to - they have an “immune support” one plus many others including Endo.
Really feel for you. We have unexplained infertility, similar ages to you. Miss carriages and no reasons coming back from now carriage bloods… we’re just about to try for our 4th implantation next month. Holding onto any hope but it’s really hard after so many set backs. Good luck with your clinic and hope they give you some answers.
I’m sorry to hear that, thankyou and you too xx
Try maca root powder
We are in the exact same age group with you but with male factor infertility and the same 2 failed round IVF, 2 FET. I am just waiting to be checked on recurring implantation failure, had a blood test done and in wait list for hysteroscopy with biopsy of lining. I've done a lot of reading on supplements for trying naturally in the mean time waiting for these tests. Like other said if we have autoimmune detected or NK cells it is treatable with steroid, clexane, aspirin etc...
Here are my notes for what I research and what my friends were advised to take by clinic on supplements. I suggest you check and verify what needed for you and your partner, the multi vitamins should contain a lot of these already
For both:
Magnesium, VitC, Zinc, Folic acid - we rely on the multi tablets. My husband takes some more Magnesium on the side.
Omega 3 1000-2000mg
CoQ10 200mg
For me: these are the 2 help with implantation
Vit D 4000 IU
Vit E 600mg 400 IU
I’m sorry to hear your troubles and thankyou so much for the vitamin info! I haven’t been taking vitamin E so will give that one a go xx
Recurrent miscarriages 
Recurrent miscarriage and high FSH level
Supplement Recommendation - missed miscarriage- Sensitive 
Hydroxychloroquine and recurrent miscarriage 
Tests for recurrent miscarriages on NHS
