IVF drugs Synarel and Decapepty cause... - Fertility Network UK

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IVF drugs Synarel and Decapepty caused menopause -has this happened to you?

JM888 profile image
5 Replies

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This happened to me. I was menstruating and ovulating and had no menopausal symptoms except irregular periods sometimes shorter or longer or sometimes 28 days.

I took Synarel from cd21 for a down regulation cycle and got the menopause symptoms within days but had to change to decapeptyl due to severe symptoms related to vision and my eyes. I commenced stimming drugs but had a cancelled cycle because my ovaries didn’t respond and then we ceased decapeptyl but my ovaries remained suppressed and blood tests revealed I had post-menopausal estrogen and progesterone levels. My hormones were perfect before I started synarel.

Ceasing decapeptyl didn’t unsuppress my ovaries and months later I was told I had reached menopause and they want me to believe it was natural but it wasn’t and the blood tests prove it.

The FS didn’t even report it to the drug companies but I did and I have found evidence online that this is a risk for a small percentage of women but I was not advised and if I had known I never would of had a down regulation cycle.

I would love to hear from other women who this may of happened to and also encourage all women to question their fertility specialist about the chances of it happening and could I ask that you provide comment about what they said.

Attached is drug information about another GnRH drug called Zoladex and it clearly states menopause is a risk for some women although rare but I wasn’t told it was a risk and if doctors aren’t reporting it such as in my case then how do they know how many it has happened to.

Who would risk damaging their hormones and entering menopause years earlier for a cycle which may not even be a success? Not me but I had no choice

Thanks and GL

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JM888
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5 Replies
Mj1986 profile image
Mj1986

I'm sorry no one has replied. Did you ever get your cycle back? I'm on synarel now and this concerns me as I have dor.

JM888 profile image
JM888 in reply to Mj1986

No never came back. What is dor?

Mj1986 profile image
Mj1986 in reply to JM888

Diminished ovarian reserve (low amh) basically I'm 35 but dont have many eggs left. My doctircwants me on synarel for 2 months and I'm worried it may out put me into early menopause.

JM888 profile image
JM888 in reply to Mj1986

So far I’m the only person I’ve found that this has happened to. Your lots younger than me. Only you can make that decision. It did happen to me.

Running79 profile image
Running79

Is that the Syranel nasal spray?!

If so I used that for my donor egg transfer and for the medicated monitored cycle (trial run before live go)

I was fine on it all I had was hot flushes

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