3rd miscarriage in 18 months. Last 2 miscarriages at 6+2, horrible coincidence or is there more to this?

[ChristineB05]

Happy New Year lovelies.

Unfortunately the end of 2019 was absolutely heartbreaking and devastating for us. 5 days before Christmas I was having medical management for my miscarriage.

Fortunately me and my OH had planned to take 3 weeks off work for the Christmas break.

But with all that time off work I read, researched and questioned why this has happened again? This is my third miscarriage in 18 months. The first was a blighted ovum and these last two were missed MC's, both 6+2. Is there some significance to this timing or simpily a horrible coincidence?

I had the first 2 MC's tested as I had D&Cs and both were normal, unfortunately I didn't the right tissue with this MC so we won't get any answers.

I would appreciate any thoughts/ ideas you may have on this?

[Hidden]

Really sorry for your losses.

I too have had a number of miscarriages (5 in total which includes 1 many many years ago, 1 chemical, one blighted ovum and two MMC). I think the timing is just a sad coincidence.

However have you had the repeat miscarriage blood work you can have done? I think its worth getting referred to the repeat MC clinic now you have had three. They will likely test your blood for clotting disorders, and may also do an MRI / hysteroscopy to check your womb.

I am sorry Christmas was such a rotten time for you and really hope with the New Year comes more positive news and your rainbow baby xx

[ChristineB05 in reply to Hidden]

Thanks lovely, I'm also sorry for your losses.

I had repeat miscarriage blood work done after my last MC. I'm in Australia and am not aware that we have repeat MC clinics. I have had a hysterocopy been on Clexane injections and progesterone pessaries the last few cycles.

I do have elevated NK cells and my last cycle was with a new clinic and the FS was not keen on me taking prednisone. I will go back to see the immune specialist, he runs separately to this clinic and see what he suggests (he is pro prednisone).

Wishing you all the best with your rainbow baby too xx

[Hidden in reply to ChristineB05]

oh gosh sorry - you know more than I do! Sounds like you have had a very rigorous check. I am so sorry this is still happening to you.

After my 3rd recent MC they put me on blood thinners etc because I had tested positive to various things like sticky blood and so when I got my next BFP I was so super excited because I was all dosed up so sure it would be a successful pregnancy - but I MC again. When I asked they just told me sometimes its just bad luck, and literally some people get loads of bad luck MC and some people never MC and sometimes there is no rhyme nor reason.

That doesn't really help, because if you are like me you will want answers, but hoping it means that your next one is a sticky one xx

[ChristineB05 in reply to Hidden]

Like you I just want answers and to understand why this is happening and what can be done to ensure a successful pregnancy.

I have told the same that it's simply bad luck. I'm sorry you have had similar luck.

Fingers crossed that our luck turns around soon xx

[DianeArnold Partner Nurse Fertility Network UK]

Hi Christine. Just wondered whether they might prescribe low dose soluble aspirin or heparin to ensure a good blood flow to your womb lining and hopefully prevent any clotting. In the UK following 3 miscarriages they refer you to a recurrent miscarriage clinic, and often the "above" is often recommended. Just my thoughts, but I do you every success next time. Diane

[ChristineB05 in reply to DianeArnold]

Hi Diane.

Thanks I have been on cleaxne for that last few cycles. Does cleaxne work the same as a low dose aspirin/ heparin?

Christine xx

[DianeArnold Partner Nurse Fertility Network UK in reply to ChristineB05]

Hi Christine. Yes it does, but releases more slowly. Diane

[ChristineB05 in reply to DianeArnold]

Thanks Diane.

Will ask immune specialist if I should switch to low dose aspirin / heparin for my next cycle.

[Hidden]

Thats not fair is it having that happen!

A friend of mine had recurrent miscarriages and it turns out she has Hughes syndrome and once she got given injections for her treatment she was fine and ended up having a baby after all that.

Best of luck to you.

[ChristineB05]

Thanks lovely it is so unfair.

Will read up about Hughes syndrome and ask my doctors as I have not come across that before.

Take care xx

[Hidden]

Hi Christine,

I’m so sorry for your losses. I’ve been through 3 ectopic and one miscarriage so I know how hard it is.

I guess you really should see the immune specialist, maybe what is missing is the corticosteroids since you have elevated NK cells.

I don’t know if your clinic checks your progesterone levels, but maybe you need more than pessaries. In my case part of my success was having progesterone pessaries and injections (Lubion). My clinic checked the day before transfer and then every time my bHCG was checked they would check the progesterone levels too.

Good luck for your next time!

XX ❤️

[ChristineB05]

Hi Lucy,

Thanks and sorry to hear about your previous losses. Hope all is going well with your pregnancy.

This last cycle was with a new clinic that is a low cost in comparison to the previous private clinics (we needed a bit of financial reprieve and immune specialist recommended we try them under his medical guidance). As the FS was against steriods I thought I should follow her advice, but I won't next time and seek the advice of the immune specialist.

None of the clinics I have used tested my progesterone before transfer. I was on Uterogestan pessaries 200mg x 3 for this cycle and actually asked the nurse about progesterone injections, her response was these are not used in Australia which I know is nonsense. I will speak to my immune specialist about this for our next cycle.

Take care and all the best 💕