Recurrent miscarriage with no diagnosis

[Dee2017]

Hello ladies. I wonder if there is anyone here who had miscarriages and all health tests came back perfect? I'm not sure what else to do to find an answer to my problem

[WeeJacs]

Me, only thing I have left to try is Nk killer cells test, but my doc is certain it's my egg quality due to Endometriosis x

[Nix44]

Hi Dee. All our general tests have come back normal, but I’m looking into doing immunology tetsing now. What tests have you had? Both our rounds on IVF so far has ended in early chemical pregnancy, also unexplained. It makes one feel so helpless if you don’t know why

[Dee2017 in reply to Nix44]

Hi Nix44. Apologies for taking so long to reply to you. And apologies on advance as it is a long story. My first two miscarriages were after getting pregnant naturally. When I saw a specialist they explained that I had fluid in the fallopian tubes which is toxic if it ends up in the uterus, so they recommended surgery and removal of tubes. When we started IVF I had AMH checked which was on the low side but still acceptable. Nothing else has been checked because there is this stupid rule that you must miscarry 3 times before tests are done. During the first Ivf I only had 3 eggs big enough to be considered, but only one was good enough for embrio transfer. I was very surprised that the clinic were prescribing treatments for 'just in case' 😔 So I was prescribed anticoagulant just in case I had problems with my blood (which I knew I didn't) At the first scan we saw a weak heart beat and the embryo measured 6 days less than it should have. This ended up in a miscarriage 2 weeks later. When seeing the specialist again he asked for blood tests (me+husband). Had also chromosome and sperm checked. Everything came back perfect. The second IVF I was prescribed a higher strength of anticoagulant 'just in case' and intralipids drips 'in case' I had problems with NK cells. I had two eggs collected which were used and transferred back as embryos. They were at the stage of 8 cells at transfer so in good health. I miscarried them 5 hours after a BFP. After the second IVF I've been asked by the specialist in who's care a was if I had my uterus checked. REALLY? NOW YOU'RE ASKING? After 2 ivf rounds you think to ask this? Why didn't they do all tests in one go? Anyway I had a hysterospocy which came back fine. So this is my story.

[Hidden]

Hi Dee, sorry to hear this! I too have suffered recurrent loss - 6 in total but my age and blood clotting could have caused them...I know of 2 of them being abnormal pregnancies - trisomy 22 at 7 weeks and severely abnormal nuchal at 14 weeks. How many have you lost? My best friend who was in her late 20s had 4 on the spin after her baby girl and before her boy. Sometimes the embryos just aren’t well or lining wasn’t receptive e for full implantation. She saw various specialist and nothing wrong with her at all. She did start taking aspirin 75mg daily at the point of ovulation but I don’t want to advise you to do that. I think you just need to keep trying as long as you have been truly tested for all blood clotting and immune issues. It took 5 losses and 3 yrs for mine to be checked properly and it’s utterly devastating xxx

[Dee2017 in reply to Hidden]

Hi Natalia44. Apologies for taking so long to reply to you. And apologies on advance ad it is a long story. My first two miscarriages were after getting pregnant naturally. When I saw a specialist they explained that I had fluid in the fallopian tubes which is toxic if it ends up in the uterus, so they recommended surgery and removal of tubes. When we started IVF I had AMH checked which was on the low side but still acceptable. Nothing else has been checked because there is this stupid rule that you must miscarry 3 times before tests are done. During the first Ivf I only had 3 eggs big enough to be considered, but only one was good enough for embrio transfer. I was very surprised that the clinic were prescribing treatments for 'just in case' 😔 So I was prescribed anticoagulant just in case I had problems with my blood (which I knew I didn't) At the first scan we saw a weak heart beat and the embryo measured 6 days less than it should have. This ended up in a miscarriage 2 weeks later. When seeing the specialist again he asked for blood tests (me+husband). Had also chromosome and sperm checked. Everything came back perfect. The second IVF I was prescribed a higher strength of anticoagulant 'just in case' and intralipids drips 'in case' I had problems with NK cells. I had two eggs collected which were used and transferred back as embryos. They were at the stage of 8 cells at transfer so in good health. I miscarried them 5 hours after a BFP. After the second IVF I've been asked by the specialist in who's care a was if I had my uterus checked. REALLY? NOW YOU'RE ASKING? After 2 ivf rounds you think to ask this? Why didn't they do all tests in one go? Anyway I had a hysterospocy which came back fine. So this is my story.

[Hidden in reply to Dee2017]

I feel your pain and frustration Dee. I had 2 miscarriages via natural conception and went through 5 cycles of ivf and 6 losses before all crucial tests were done. It angers and annoys me as it seems these so called experts are so busy cramming in as many patients as possible and thinking primarily about money instead of individual care. It’s great there’s nothing wrong and I honestly think you will get there successfully xxx

[Dee2017 in reply to Hidden]

Thank you Natalia. I feel the same. The most important thing for them is to get more money. Forget about the empathy and the humanity of the whole process. I'll have to look into changing the clinic 🤔 xx

[Tiffs]

I had 3 miscarriages and too started taking 75mg aspirin from ovulation. We had an appt at the micarriage clinic where we were advised to do this as well. I am now 13 weeks pregnant and all looks great! I too am not saying this is the answer but they certainly think it helps with platelets and blood clotting and it’s worked for me!

[Dee2017 in reply to Tiffs]

Hi Tiffs. Apologies for taking so long to reply to you. And apologies on advance ad it is a long story. My first two miscarriages were after getting pregnant naturally. When I saw a specialist they explained that I had fluid in the fallopian tubes which is toxic if it ends up in the uterus, so they recommended surgery and removal of tubes. When we started IVF I had AMH checked which was on the low side but still acceptable. Nothing else has been checked because there is this stupid rule that you must miscarry 3 times before tests are done. During the first Ivf I only had 3 eggs big enough to be considered, but only one was good enough for embrio transfer. I was very surprised that the clinic were prescribing treatments for 'just in case' 😔 So I was prescribed anticoagulant just in case I had problems with my blood (which I knew I didn't) At the first scan we saw a weak heart beat and the embryo measured 6 days less than it should have. This ended up in a miscarriage 2 weeks later. When seeing the specialist again he asked for blood tests (me+husband). Had also chromosome and sperm checked. Everything came back perfect. The second IVF I was prescribed a higher strength of anticoagulant 'just in case' and intralipids drips 'in case' I had problems with NK cells. I had two eggs collected which were used and transferred back as embryos. They were at the stage of 8 cells at transfer so in good health. I miscarried them 5 hours after a BFP. After the second IVF I've been asked by the specialist in who's care a was if I had my uterus checked. REALLY? NOW YOU'RE ASKING? After 2 ivf rounds you think to ask this? Why didn't they do all tests in one go? Anyway I had a hysterospocy which came back fine. So this is my story.

[Dee2017]

Hi ladies. Apologies for taking so long to reply to you. And apologies on advance ad it is a long story. My first two miscarriages were after getting pregnant naturally. When I saw a specialist they explained that I had fluid in the fallopian tubes which is toxic if it ends up in the uterus, so they recommended surgery and removal of tubes. When we started IVF I had AMH checked which was on the low side but still acceptable. Nothing else has been checked because there is this stupid rule that you must miscarry 3 times before tests are done. During the first Ivf I only had 3 eggs big enough to be considered, but only one was good enough for embrio transfer. I was very surprised that the clinic were prescribing treatments for 'just in case' 😔 So I was prescribed anticoagulant just in case I had problems with my blood (which I knew I didn't) At the first scan we saw a weak heart beat and the embryo measured 6 days less than it should have. This ended up in a miscarriage 2 weeks later. When seeing the specialist again he asked for blood tests (me+husband). Had also chromosome and sperm checked. Everything came back perfect. The second IVF I was prescribed a higher strength of anticoagulant 'just in case' and intralipids drips 'in case' I had problems with NK cells. I had two eggs collected which were used and transferred back as embryos. They were at the stage of 8 cells at transfer so in good health. I miscarried them 5 hours after a BFP. After the second IVF I've been asked by the specialist in who's care a was if I had my uterus checked. REALLY? NOW YOU'RE ASKING? After 2 ivf rounds you think to ask this? Why didn't they do all tests in one go? Anyway I had a hysterospocy which came back fine. So this is my story. Thank you all xx

[Aleelilook]

I’m having the endometrial receptivity test and one to test the NK cells in my uterus during a medicated mock FET cycle with my private clinic and I’m waiting for all the normal blood tests on the NHS. Might be worth a look? Xx

[Dee2017 in reply to Aleelilook]

Hey. Thank you for your reply Aleelilook. We had quite a few tests done. I wrote a loooong description of our journey earlier today to give you a small perspective on our situation xxx

[Aleelilook in reply to Dee2017]

Ah yes I read that, I’m so sorry you’ve had such an awful time, but the ERT actually takes a biopsy at the time you’d have transfer to test if the time they’re popping embryos back is actually the right time for your uterus xx

[Dee2017 in reply to Aleelilook]

Thank you. I'll have to push for this test and whatever other tests there are. I'm actually thinking of changing clinics........