Zoladex and a bit of a dilemma - Fertility Network UK

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Zoladex and a bit of a dilemma


Hello ladies,

I really hope you can help. I have a history of endometriosis and fibroids and since having a zoledex injection last year became peri-menopausal at 39. I was planning of having a partial hysterectomy (leaving my ovaries intact) next month but as i am 39 with no children the consultant advised another course of zoladex.

I'm very worried about all of this because the next course of zoladex may put me in permanent menopause so i'm unable to have children but if i have a partial hysterectomy the chances of having children diminish too. I've discussed freezing my eggs but wasn't given much information on this option.

Has anyone else been in this dilemma, i really don't don't know what to do


7 Replies

Hi Curly22,

Sorry for the situation you are in. I'm not the best person to give an advice but having had fibroids and endo and still battling some of it now, I can fully relate.

My question will be have you tried myomectomy or some other medical ways of removing fibroids? If Zoladex is making you go menopausal I believe it's temporal (correct me if I'm wrong).

I would suggest you get second and third opinion before doing a hysterectomy.

Wishing you the best in this journey.

Curly22 in reply to kumkums

Hello KumKums,

Thank you so much for replying, even typing it all out helps :)

I had a myomectomy 2 years ago to remove a big fibroid but there is still one there that they were unable to remove. You're right about zoladex causing temporal menopause but still peri-menopausal a year later. It's a real dilemma, think i'm going to see a different doctor and see whether i can get some more advice.

Thanks again for your good wishes xxx

kumkums in reply to Curly22

I see from the aspect of peri-menopausal. However relating from your experience, I strongly think you should ask your consultant questions and get other opinions. I had 8 fibroids, and 1 endometrioma removed and a bit of separation of stuck together organs done 3 years ago. The fibroids were big, I had 3 big ones like a size of very big lemon and 4 small ones like big grapes and 1 like a size of lime. I am just creating a visual representation of things so that you can relate, because I believe you should not rush into hysterectomy. I had decapeptyl and I didn't even know what was called menopause then, so maybe I didn't pay attention to side effects, but I was fine after it.

Also I found out that Asian/ Africans/Afro-American doctors tend to deal well with fibroids because it's something more prevalent in their region.

I dont know too much about the long term effects of Zoladex but it sounds as if the consultant wasnt too keen on you having the partial hysterectomy in case you want children in future which makes me think it would still be possible if you have another zoladex injection. However this is massive guess work and if I was you I'd ask to have a another conversation with your consultant and write all of your questions down. The egg freezing thing may or may not be possible and I know that generally you would need high numbers to have a chance od success but not only that high quality eggs which as we get older our egg quality dimishes too. Best of luck with it all!xx

Curly22 in reply to Cinderella5

Thank you :) unfortunately i'm not seeing my Consultant until another 6 months, may check whether i speak to his secretary just in case :) x

Cinderella5 in reply to Curly22

Well even if you could get a chat with the secy and see if she could do something to help, even a telephone consultation?xx

Curly22 in reply to Cinderella5

I hope so, am on the case now, thanks very much for listening x

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