A Simple inexpensive Blood test can Predict whether you carry a CV risk in future or/and you carry a risk of type 2 Diabetes/metabolic synd

[namaha]

I was interacting yesterday with one of my close Cardiologist Friend (we were school friends), he tells me that one simple blood test- least expensive which people don't do- can predict if you carry any CV risk or type 2 diabetic risk..

For an existing type-2 , it can predict to what extent the beta cells are functioning and if the progression is slowed down due to any life style change / any treatment ! He also sent me some links which I am attaching at the bottom of this message.

What he explained me, I am just putting it briefly :

The Test is called "High Sensitivity C-Reactive Protein popularly known as hsCRP"

(1) the test is an overall indication for how this wonderful machine is working!

(2) It would indicate the overall inflammation inside your body which (you may not feel or may not have any visible symptoms)

(3) if you are obese , you must do this test as frequently as possible to see the trend preferably every 3 months

(4) If you are type 2, you must check every 3 months. The trend will indicate the progression of your beta cells status. hsCRP will keep increasing if more and more beta cells are getting damaged.

(5) If you are on LCHF diet and if you are exercising regularly (both Aerobic & Resistance) and /or taking some diabetic medicines/ Statin, chances are that your hsCRP may come within normal limits. Therefore , if you are practising LCHF to counter Type 2 without any medication , it is ideal to check hsCRP at regular intervals to ensure that you don't have inflammation. High level of inflammation could carry a CV risk and gradual damage to beta cells.

(6) He also said that Obesity and / or type 2 are notorious in the sense that it is a progressive disorder and hsCRP status can serve as an indicator of the status!

(7) hsCRP less than 1 mg/L means normal.

If 1 to 3 mg/L , you carry a moderate risk of CV/ metabolic syndrome!

If more than 3mg/L, you carry a high risk

If more than 10 means it requires intervention !

Does not matter whether you are obese or not , if you are type 2 or not, please always do this test at regular intervals and keep a record to see the trend. In case it is persistently more, you should seek medical advice!

ahajournals.org/doi/10.1161...

ncbi.nlm.nih.gov/pubmed/164...

jaoa.org/article.aspx?artic...

[sandybrown]

This post was edited what was removed or added?

Is this test freely available for every one any where in the world?

At what age do you do this test?

Sorry to ask these questions, at 72 I need to get full facts!!!

[Activity2004 Administrator in reply to sandybrown]

Asking questions about anything you want to know is okay. 😀👍

[namaha Administrator in reply to sandybrown]

Dear Sandy

You need not worry if it is edited or not?

The person who posts has the right to add/ delete / edit if he finds some error at a later stage ! ☺️

HU has got the right to totally remove a post if they want for some reason!😀

As regards to the hsCRP, you can check at any age any time and at the time of your normal health check up.

It would indicate the extent of inflammation you have in your body which could be a risk factor for CV risk and metabolic syndrome.

At times it could be high due to some underlying infection. But if it persistently remains high on several occassions, it may indicate the progression of metabolic syndromes.

[nyonyo]

Mine was 0.5 mg/L, i did it 6 months ago, but i was confirmed a full-blown diabetic almost 2 years ago

[namaha Administrator in reply to nyonyo]

Not sure , if you measured for the first time or you had any trend of past readings !

In any case, there could be exceptions here and there because of some internal and external factors.

That is the reaon why there are RCT's covering a large group of people covering age groups from different race and different locations. And the result is in terms of % and Medians l.e how most people react.

You may like to go through the studies in the links and many several studies on the subject available from several agencies!

[nyonyo in reply to namaha]

For the first time, but my point is, it can not be used to predict the risk of developing type 2 in the future, as i already had it when it was done, and it can not predict the extent of damage on the beta cells since my HOMA B was only 54% at that time, so i'm not sure if i'm free of cv risk in the future, though my result was well within the normal value

[namaha Administrator in reply to nyonyo]

you may like to add this test to your regular package whenever you visit a lab. Very inexpensive test indicating the extent of inflammation in the body. I could see several studies on hsCRP being a risk factor for CV!

Will also send you a link on hsCRP correlation with beta cells.

[namaha Administrator in reply to nyonyo]

One more study on hsCRP-

which you may like to go through ! Further , you must go through the summary of the findings of all the cohort studies on hsCRP documented in my original post!

ncbi.nlm.nih.gov/m/pubmed/1...

[nyonyo in reply to namaha]

ehm...the subjects of this study are 4270 non-insulin-treated patients , i'm on basal insulin only, their BMI are >30, mine is <25, i don't know whether or not those make a difference

and the conclusions are: Our results indicate (not PROVE) that hsCRP may (not MUST) be used as a cardiovascular risk marker in patients with type 2 diabetes mellitus and should be "evaluated in further prospective studies".

[namaha Administrator in reply to nyonyo]

I am not sure whether this is applicable for type 1 where some one is already on insulin.

And this is only one study you are referring, had suggested you to go through the first link of my original post which summarises all studies so far conducted..

And you may please get guided depending upon your health condition and after consulting your physician !

[nyonyo in reply to namaha]

Not sure whether you think i'm type 1, but i'm type 2. and I have read all those studies you posted before you posted, even more

[namaha Administrator in reply to nyonyo]

Sorry , I mistook you as type 1, when you said "I am on basal insulin only".

Good luck ! Intention is to learn and share.. help each other with info and inputs.. ☺️

[Aajkal]

Hscrp test is to measure risk of CV & not for detection diabetes. I am a diabetic and my hacrp is 0.69 which is done last week. My Hba1c is 6.00. I am still taking 1 tablet of Reclide MR 30 before lunch. That is the only medicine. Earlier I used to take 500 mg Glimisave M2 before lunch & dinner. Due to major changes in my life style, I could reduce the medicines

[sandybrown in reply to Aajkal]

Inflammation and CVD, yes!

BY having hsCRP of 0.69, (what is the unit of measurement?) are you at any risk of CVD?

It is good that your life style change has helped you to reduce your medication.

Life style change can control type 2, excellent.

Would it be possible for you let us have some information on your life style change?

[Aajkal in reply to sandybrown]

Morning a glass of smoothie. No tea/coffee. Lunch at 12.30/1 & dinner at 8pm. U will notice that I observe intermittent fasting of 16 hrs daily. No non-veg. No junk food & no milk & milk products. At 4.30pm I take a cup of tea without sugar & with soy milk. That’s it. I am trying hard to get rid of existing single tablet. One more thing, I am regularly going to gym & lifting weights & also treadmill. Daily workout is 45 minutes.

[namaha Administrator in reply to Aajkal]

It is good to see your hsCRP which is an indication of overall inflammation is within limits. Life style changes, Exercise plays a major role and though some medicines are also known to reduce inflammation, it is always better by natural means !

I am attaching few more studies which indicate a direct link between type 2 diabetes and hsCRP and one of the studies from ADA.

care.diabetesjournals.org/c...

academic.oup.com/jcem/artic...

[namaha Administrator in reply to Aajkal]

Great!

Which indicates you don't seem to have CV risk as of today.

With regards to normal values, if you take a LCHF diet / exercise regularly

(you please refere point no 5 of my post) , your value may come within normal range.

Also there are many allopathy anti- diabetic medicines which seem to keep hsCRP supressed within normal range. Not sure whether this is good or bad !

[barani19 Administrator]

Thanks for this useful information namaha . Appreciated!

[makarim]

Thanks for this information.The discussions are very informative .I do not know how milk effects BS.skimmed milk has only 5 grams carb in 100ml.Though I am in LCHF diet and only take gliclazide 30 mg once during 24 hours.Thanks every body.

[namaha Administrator in reply to makarim]

100 ml Skim milk may not matter much if not combined with other Carbs at the same time because the Glycemic load is low... ....Why not you check your blood glucose with a Glucometer at home. .... Seeing is believing !

[makarim in reply to namaha]

Thanks for the response.Sir, I usually check check my BS every alternate day andit rangesfrom 85 t0 95 FBS.Ofcourse I have not checked after taking 100ml of milk.I shall check .Thanks.

[namaha Administrator in reply to makarim]

But why are you not taking full cream milk, which is more healthier than skim milk, and why not full Cream Curd or Yogurt which is still better and Greek Yogurt with low carb , high protein is the best.

For digesting milk which is Lactose, you need an enzyme from your body called Lactase to break it in to Glucose & Galactose.....if you have little deficiency of the enzyme Lactase, you may have a bit of lactose intolerance!

Whereas , if you take curd, you get lactic acid / lactate, easy to digest and you get valuable probiotics such lactobacillus which is good for overall health!

[namaha Administrator]

And let me tell you my hsCRP touched 2.5 mg/L a year back....

And today it is 0.1 mg/L...

Only by dietary changes....

Now I know how to tame it...

Chronic inflammation is bad for arteries, bad for beta cells, .....bad for diabetes...