I take 2 mg Glimepiride + 500 mg Metformin tabs.& 30 units Insulin in the morning & same dose of talets + 10 units insulin in the evening

When ever I find fasting sugur level more than 120 I used to take 1 mg more glimepiride . Similarly whenever sugur level is less than 80 I used to reduce 1mg glmepiride . I have recieved advice recently that effect of increase or reduction of glimepiride will be felt only next day and hence to make appropriate changes in units of insulin I am not quite convinced of this advice Glimepiride produces effect within about 1 hour and not next day . What is the correct position?

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  • In my opinion,it is advisable to stick to a prescribed dose until the next review by the physician.You may think of better diet control or more exercise but not change the dosage of medication.Also,I too use Accucheck,but only to monitor the general trends.

  • Half life period - Probably the medicine works for 24 hours

  • === GENERAL ADVICE====================================

    The text below is a "COPY&PASTE STUFF" from my previous replies to some others.

    IF YOU HAVE ALREADY SEEN IT, KINDLY IGNORE THIS. Otherwise read CAREFULLY.

    ================================================ =====

    TAKING MEDICINES ALONE WILL NOT BRING DOWN BLOOD SUGAR ALWAYS. THAT IS WHY PATIENTS ARE FORCED TO MOVE FROM EXERCISE TO DIET CONTROL TO LOW DOSE TABLETS TO HIGHER DOSE TABLETS TO INSULIN INJECTION AND COMBINATIONS OF THESE. YOU HAVE TO CHANGE YOUR FOOD HABITS & LIFE STYLE ALSO TEMPORARILY TILL CURE.

    You too can EVEN cure your diabetes yourself like me by following the Long Wheat Mash Diet Regimen (LWMDR). Google search 'LWMDR' or 'GEORGE CURED DIABETES' for details.

    Diabetes is a fundamental disorder. It is comparable with low voltage in an electric circuit. In both cases all connected subsystems will under-perform and will fail in due course. It will affect SEX life also, if diab is not contained. Diab impairs the glucose (SUGAR) & oxygen supply to ALL CELLS of the patient. You cannot compensate the resultant weakness with liquor, food or medicines.

    A DIABETES PATIENT (also known as A DIABETIC) need NOT starve. PROPER or APPROPRIATE food can be eaten EVEN FULL STOMACH THRICE DAILY! Try to understand diabetes & conquer it like me.

    While following the Long-wheat diet explained in the article referred below, non-vegetarians can have MEAT/FISH/EGG in moderate quantities as side-dishes/curries.

    I was diabetic from 2006; but NOT diabetic from 2009. I studied Diabetes thoroughly, because it was to solve MY problem.

    Do you want to see my experience and blood sugar history from 2006 to 2013? Those are reported at: appropedia.org/Diabetes_mel... If you want only HOW TO DO, GO TO appropedia.org/Diabetes_mel...

    appropedia.org/File:BloodSu...

    Please read MY REPLIES part 1, 2, 3 & 4 to question AT diabetesindia.healthunlocke...

    Like a licensed driver helping a learner, I can guide you to cure Diabetes because I am experienced by curing my diabetes (Type-2) in 2009.

    Please report your future experience (good or bad) here for the benefit of others.

    IF ANY ONE START LWMDR, DO NOT STOP PRESENT MEDICATION ABRUPTLY; IT WILL CAUSE THE BLOOD SUGAR TO SHOOT UP. TAPER DOWN (REDUCE) MEDICINES GRADUALLY DEPENDING ON REDUCTION OF BLOOD SUGAR, AS PER YOUR DOCTOR'S ADVICE OR BASED ON YOUR JUDGEMENT IN CONSULTATION WITH ME. LWMDR is not just drinking Long Wheat Mash, it is a Diet Regimen. One has to follow associated restrictions also since Long Wheat does not have muscle power like chemical drugs.

    Curing Diabetes is like driving, swimming or bicycling; guidance & supervision are highly desirable while learning.

    Please report progress for the benefit of others.

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  • Where can we get LWMDR ? We are in Tamil nadu, Salem... Please post your contact no... Your advice seems very much valuable.

  • LWMDR is not a thing available across the counter. It is the abbreviation of Long Wheat Mash Diet Regimen.

    ===LWMDR

    Yes Diabetes Mellitus (DM) can be regressed/retarded & finally stopped. Follow the Long Wheat Mash Diet Regimen - treatment for permanent cure. It cured my diabetes in 2009.

    I was diabetic only for three years from 2006. Lab results are published in the Web Article. More than 28,000 people have read it.

    Just search Long Wheat in Google; my article will come as the FIRST one out of 116,000,000 results!!(As on 5Aug2013)

    Long Wheat Mash Diet Regimen (LWMDR) Modus operandi

    In order to obtain initial conditions, get FBS, PPBS & HbA1C tests done before hand.

    1. Facilitate required (optimum-NOT maximum) rest to pancreas by TOTALLY AVOIDING sweet intake; avoid fruits as well till getting CURED.

    2. Substitute break fast and dinner by long-wheat kanji (porridge/mash) with a pinch of salt as required and curries (hot/sour side dishes - with no sweet). Continue lunch as it is (with oil, fat, potato, tapioca & sweet restrictions). Take all the three meals stomach full. As body extracts micro medicine from LWM, intake is to be equispaced & voluminous; hence LWM swapped with staple part of breakfast & dinner.

    3. Reduce food intake frequency by postponing &/or combining and filling the gaps with plain water. May eat or drink more if number of intakes is three (3) or less including refreshments (snacks, tea, coffee, cool drinks etc.) in a day. Reduce oil & fat intake.

    4. Brisk, medium or at least normal walk preferably for an hour daily.

    Caution

    1. Buy & use only unbroken long-wheat lest you should be cheated.

    2. If blood sugar does not start decreasing in a month, avoid smoking & liquor if you are in the habit of having them.

    3. Monitor blood sugar regularly - PPBS weekly, FBS at least monthly and HbA1C quarterly.

    4. If already on tab. or insulin inj. one must continue those & monitor blood sugar MORE FREQUENTLY, preferably daily, at least FOR A WEEK. Else one may slip into low blood sugar problem (hypoglycaemia?).

    Neglecting any of the above eight points (four of modus operandi and four of caution) is similar to removing one of the legs of a table.

    As you approach CURE, progress will be slower.

    IF ANY ONE START LWMDR, DO NOT STOP PRESENT MEDICATION ABRUPTLY; IT WILL CAUSE THE BLOOD SUGAR TO SHOOT UP. TAPER DOWN (REDUCE) MEDICINES GRADUALLY DEPENDING ON REDUCTION OF BLOOD SUGAR, AS PER YOUR DOCTOR'S ADVICE OR BASED ON YOUR JUDGEMENT IN CONSULTATION WITH ME. LWMDR is not just drinking Long Wheat Mash, it is a Diet Regimen. One has to follow associated restrictions also since Long Wheat does not have muscle power like chemical drugs.

    Curing Diabetes is like driving, swimming or bicycling; guidance & supervision are highly desirable while learning.

    Please report progress for the benefit of others.====

    See also healthunlocked.com/diabetes... MY POST 1: Diabetes cured. Ask me more, in case of doubt.