Blood work for PD

[YOPDUpsideDown]

Hi there! I am about to do blood work to understand if I have some deficiency that is not helping my PD symptoms. So far, I was recommended to do these exams from one of our members here but wanted to ask everyone anyways what do you recommend to be checked:

HsCRP

Homocysteine

TSH

Standard Lipid Panel

HBA1c

Comprehensive Metabolic Panel

Ferritin

Iron and IBC

Vitamin B12

CBC with Auto Diff

Uric Acid

Vitamin D 25 OH

Omega Check

DHEA-S

F2 Isoprostanes

Methylmalonic Acid

Thanks for your feedback!

Rita

[Esperanto]

Given the common deficiency of vitamin B6 in PWP, I recommend that you have this checked (regularly) as well. Additionally, an elevated homocysteine level can also indicate a possible deficiency of vitamin B6.

[Daisies22 in reply to Esperanto]

Hello Esperanto,I have got a question. How do I calculate the dose of vitamin B6 that I have to take if I were deficient?

Do you take into account gender, weight, and BMI or "we are all equal"?

Thank you in advance.

[Esperanto in reply to Daisies22]

Unfortunately Daisies22, there has been insufficient research conducted on this topic. In addition to the usual individual differences, âge and the factors you mentioned do play a role, but they are not determining factors. The situation is different for the medication containing carbidopa, which interacts with vitamin B6; however, there are also no scientifically validated guidelines regarding this interaction.

This lack of information prompted me to start a database for B6 test results, which has shown that an intake above 5 mg can often lead to significant overdoses. This may be due to the long half-life of vitamin B6, which is about a month, leading to accumulation in the body. Keep in mind that the daily recommended amount is approximately 1.5 mg. The impact of the medication appears to be less significant than often assumed, according to the test results. Various B vitamins, including vitamin B2 (riboflavin), play an important role in the absorption and metabolism of vitamin B6.

I encourage you to monitor the degree of deficiency (or overdose) by getting tested regularly! My advice is to start with a modest dosage.

New (and old) test results are very welcome. I will incorporate them into the aforementioned database.

(healthunlocked.com/cure-par...

[Daisies22 in reply to Esperanto]

Thank you for your reply!I will definitely share with you my blood test results - I had the blood test done a month ago when I was hospitalised for a week but the test results still have not arrived at home.

[Ghmac in reply to Esperanto]

Do you have a resource I can give our MD about Vit B/PD and C/L relationship. I struggle to explain to him why I think it is important to test for specific Vit Bs.

[Esperanto in reply to Ghmac]

This review summarizes the studies that evaluated the role of vitamins (A, B, C, D, E, and K) in PD:

ncbi.nlm.nih.gov/pmc/articl...

And the B vitamins in particular:

ncbi.nlm.nih.gov/pmc/articl...

The balance in your vitamin/mineral household also affects your C/L medication. Specifically, the interaction between B6 and carbidopa is, as the following study shows:

researchgate.net/publicatio...

Don’t forget the contribution of park_bear about this:

healthunlocked.com/cure-par...

[Ghmac in reply to Esperanto]

Thank you so much.

[YOPDUpsideDown in reply to Esperanto]

Thanks a lot!

[MPPD]

can vitamin supplements cause low iron, low transferrin, low TIBC, and low saturation? (These are all iron markers)…. I take the following vitamins: B complex, high dose B1, magnesium, multi vitamin, Q10 and fish oil

[chartist in reply to MPPD]

Having low vitamin A can cause low iron, low transferrin and low TIBC.

Art

[Patient100]

Usually iron levels are interpreted along with hemoglobin (Hb) levels to determine whether you are anemic due to iron deficiency. What are your Hb, MCV and MCH levels? Low vitamin B12 can also cause anemia, but I'm not aware of any other associations of low iron with vitamins or supplements.

[ktbooks77]

Dr Laurie Mischley's Parkinson's School has a series of videos about what labs to order and she also spells out her reference ranges and lays out how to treat each item. She recommends not only blood tests, but also hair analysis. You can often get a free trial her program, but at $10/month her vast knowledge shared wide and deep is entirely worth it. I had deficiencies from lithium to DHEA to B12 and. more that are now corrected. Over the last 5 years I have been following her, my PD symptoms have dropped significantly. Good luck! pd-school.teachable.com

[YOPDUpsideDown in reply to ktbooks77]

Thanks a lot! I actually got this blood work check list from someone who had appointments with Dr. Laurie. She is definitely a great reference in this field.

[Nikkiheat2]

A couple of easy ones for us - urine pH strips and urine test panel strips from Amazon. My husband had some things off there we've been correcting with diet. We also did microbiome, organic acid, heavy metal and leaky gut. When you have 200 or 300 biomarkers to work with, you can really start to see patterns and it gave us a lot to work with. We've been going through the markers one by one and trying to get them into normal range.

It is interesting that the formal medical diagnosis was he has PD. Take these pills. The local support group has talks on "stages of Parkinson's", like going downhill is inevitable.

Yet detailed functional medicine testing has showed my husband had well over 20 biomarkers out of range, and individually most of those biomarkers have some kind of known treatments, usually diet, supplement or herbal. All the research studies show PWP seem to have a lot of out of range blood, urine and gut test results, and they aren't always the same from person to person. If we fix up the test results on a personalized basis, can he reverse the PD symptoms? It has been slow going but we have been making progress. We've been using the test results and a lot of chats with Google's AI to help find the imbalance patterns and suggest possible solutions.

[al315]

I got the attached list from Seattle Integrative Medicine (Dr. Laurie Mischley's practice).

blood work list