Confused about diagnosis

[Sgturner8931]

My calprotectin levels are over 400, which the GI doctor said indicates Crohn's or some other form of IBD, but the doctor that did the endoscopy and the colonoscopy found an almost healed peptic ulcer and said there are no signs of Crohns in my lower digestive tract and that I DO NOT HAVE CROHN'S. If that's true, what else could cause the highly elevated calprotectin level? BTW, I have also been diagnosed with pancytopenia and have lost 20 pounds in the last 3 months, not on a diet.

[FRreedman]

A calprotectin level of 400 certainly indicates further investigation is necessary to determine what form of IBD, if any, is present. You say you are suffering with pancytopenia which is a deficiency in your blood cells, which could affect the calprotectin levels found. You also say there are indications of a peptic ulcer, which would also cause an increase in calprotectin levels. I would go back to the GI consultant and ask him what differences would his diagnoses be, now he has the report from the endoscopist. My personal view is he will ask you to retake the calprotectin test in about two months time, allowing everything to settle down first. Good luck.