Not sure if anyone can help, but I recently did aFaecal calprotectin test which came back at 809 ug/g. However all my bloods were normal including CRP. I also had a colonoscopy, MRI and capsule endoscopy in 2021 and all came back normal. So have been diagnosed with IBS- D by gastroenterologist. My symptoms worsened in December. The gastroenterologist suggested repeating faecal calprotectin and bloods through my GP which I did in Jan this year. Which is when my faecal calprotectin came back high. I trying to get my gp to send the results to my gastroenterologist as I want to see what they advise, but they didn’t. I have however been referred for a colonoscopy but still waiting to hear. I would like to know what peoples thought on this is considering my colonoscopy was clear in 2021. Can IBS cause the high calprotectin? If I do get a colonoscopy appointment is it worth repeating? I am worried about The Faecal calprotectin results. Is 809 something to be concerned about? would crp not be raised too if its IBD.
What else could causes this? thank you, any advise would be much appreciate
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Jutme
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I'm new to this but I wanted to let you know that you are not alone as I went through something very similar with high calprotectin levels around 2000. I have been suffering with varying symptoms over the last 5 years and have only recently been diagnosed. I too had a clear colonoscopy 4 years ago, blood tests come back as normal and a capsule endoscopy only last November and nothing was found. I pushed for a second colonoscopy due to worsening of symptoms and I can say that it is always worth having the procedure when it is offered to you! I didn't get results until my second colonoscopy so sometimes things can be missed.
Hi JutmePlease to not be influenced by your GP not sending your results to your consultant. Put in a request for a copy of these results yourself from the GP, you are entitled copies of any test results and medical history. I personally always request copies for all tests regardless of GP or hospital, along with a copy of every clinic letter sent to my GP after every appointment. I do keep copies of CT, MRI etc scans.
Get your results and send them to your consultant yourself and request advice, usually they are very good. Given this result differs from the one the consultant did originally they will be interested in the difference.
I always request slight sedation on colonoscopy end endoscopy.
None of my tests have returned a satisfactory result and my gastroenterologist continues to search for answers which I am grateful for.
Good luck in finding out some answers amd treatment.
Having a raised calprotectin level generally means you have active inflammation in your body. This is generally associated with inflammatory bowel diseases (IBD) such as Crohn's disease or ulcerative colitis. The higher the level of faecal calprotectin the more inflammation present in your intestines.ibdrelief.com/learn/what-is...
Calprotectin levels of 50–200 micrograms per milligram (μg/mg) are usually normal. This level may indicate a slight elevation of calprotectin levels, but it is not usually enough to warrant further investigation. Calprotectin levels higher than 200 μg/mg may indicate an inflammatory condition.
Fecal calprotectin (FC) is more specific than CRP for intestinal inflammation, except in isolated ileal disease. FC better correlates with endoscopic findings than CRP and is useful in monitoring Crohn’s patients for postoperative recurrence:
Hi my calproprectin level was 5937. I had a colonoscopy done in December and my diagnosis is ulcerative colitis. The calproprectin reading is the level of inflammation which is what my IBD team have told me. If it’s high then probably a different treatment plan might have to be introduced.
Time to get a new GP? You are entitled to quality care if you pay for medical services and that means your GP and specialist talking and keeping you in the loop. If you don't get the care you need go elsewhere if that is a possibility. I don't know enough about the tests to know which one is likely to be in error, you should be able to ask your GP and specialist for answers and don't stop until you get them. All the best getting the right treatment.
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Repeating Colonoscopy after normal results? 
High calprotectin, but no symptoms?
IBD??
What now.... 
