Acalabrutinib

[Jsceltic67]

Hi there.Has anyone been on Acalabrutinib iam starting treatment today,1 tablet per day 100mg,then go for blood test end of month and see doctor to see if they can up it to 2 tablets per day. Thanks John.

[Walkingtall62]

Hi, I was on Acalabrutinib for quite a while. Had no problems at all, it was almost ‘my friend’. The only reason I changed was because the capsule was changed to a tablet and I don’t get on with one of the new ingredients (fillets). Enjoy the journey and all the best

[Jsceltic67 in reply to Walkingtall62]

Thanks very much for the information, appreciate it.Thanks John

[Panz in reply to Walkingtall62]

If you develop a headache remember just a little caffeine will take care of it. It is a very good medicine.

All the very best!

Panz👍🙏😊☕️☘️

[Stamphappy]

👋 Just want to wish you the best! 😊

[CLLpa]

i hope it goes well

[Nucleusman]

read the leaflet which comes with tablets. A very good and effective drug after 2 years I am in remission but must continue taking. Only side effects I have experienced are bruising which comes and goes also more susceptible to other cancers so stay out of the sun and use factor sun cream every day. It actually works

[Nucleusman in reply to Nucleusman]

factor 50 sun screen

[Jsceltic67 in reply to Nucleusman]

Thanks very much for the reply appreciate it.John.

[Kwenda]

Many people also take Allopurinol for the first month as you need to flush out the waste products safely

Allopurinol is a medicine used to lower levels of uric acid in your blood and thus protects the

kidneys..

Some also take Co-Trimoxazole

To protect against any infection, particularly any lung infection.

Normally just THREE pills a week only

And don't forget that Shingles is always a threat so take Aciclovir

To protect against Shingles.

Having said that the Acalabrutinib works for myself and many people with minimal side effects.

Dick

[Daisy396]

I’ve been on acalabrutinib for 2 years now. My only issue is joint and muscle pain, I am in partial remission with no other serious issues. Good luck , I wish you all the best on this medication.

[Unglorious in reply to Daisy396]

I too used to experience joint and muscle pain when I first started Acalabrutinib, but in my case I think it had something to do with being on a statin at the same time that contributed to the aches. Once I discontinued the statin the pain abated. One of the side effects of statins is muscle pain. Are you taking a statin?

[Jsceltic67 in reply to Unglorious]

Not on stating,just a blood pressure tablet only 2.5,thank you for the reply. John.

[Daisy396 in reply to Unglorious]

No, I’m not on any other medication. The joint and muscle pain is pretty bad. But the Acalabrutinib is working so I tolerate it.

[Unglorious in reply to Daisy396]

Try doing stretching exercises and using a massage gun, recommended to me by my physiotherapist.

[Ajstotts in reply to Daisy396]

I had the same muscle/skeletal pain after approximately 1.5 years of calquence. After 6 months of pain I started taking colostrum. Pain is gone. Coincidence? Maybe, but I won’t stop my daily dose of colostrum.

[Westie11- in reply to Ajstotts]

Thanks to your reply I am now wondering if my pain isn't going away due to being Acalabrutinib which never occurred to me until reading on here. I pulled a muscle in top part of my arm about 3 months ago and it isn't getting better. Also I suffered for almost a year with sciatica, pain in right buttock and it finally went about 2 months ago but there was always a little bit of discomfort at times as if saying, careful, I am still here!! Now it's back and having to take pain killer. Now wondering if this is all related ? (Been on Acalabrutinib 2 yrs)

[uihwki]

Been on acalabrutinib for 7 years. The headaches were pretty bad for the few weeks. Took Excedrin Tension Headache tablets at the recommendation of my CLL specialist - problem solved. It's been a miracle drug for me!

[Bobby9toes]

Hi John, I have been taking 100 mg tablet for one year for SLL. After 6 months, I was already in remission. I will need to continue taking it for life. In the beginning, I did have headaches but caffeine and sometimes Excedrin for tension headaches took them away. I was also on Allopurinol at first, but quit due to a bad reaction to it. I also take 400mg twice a day of Acyclovir to prevent shingles. It was a miracle drug for me. Best of luck to you. I’m sure you will do just fine on it.

[Jsceltic67 in reply to Bobby9toes]

Thanks Bobby,appreciate the reply,it really helps me feel alot better,it's great we can talk to other people who are going through the same thing. Thanks John.

[Se_re_n_geti in reply to Bobby9toes]

About the Acyclovir: Are you take it as long as you take Acala? Thanks, Maria

[Bobby9toes in reply to Se_re_n_geti]

Yes, I will be. My doctor told me it’s an anti viral medication that will protect me from viruses such as shingles. I have no side affects from it.

[Se_re_n_geti in reply to Bobby9toes]

Thank you very much for the quick reply. I have been on Acala about a year, first line treatment. Al the time with Acyclovir. I just wondered how long to take it. I hope it protects me from the viruses around here, especially in the winter season. It seams like better to continue with that.

[Sunrisejoy]

Hello, thanks for posting, hope you are well.Starting it in a few weeks. Same, starting at 100 mg because I have permanent afib.

[Jsceltic67 in reply to Sunrisejoy]

Hope it works well for you as well,only on 1 per day for 2 weeks to see how I do.ok so far,back on 22nd Jan blood test and see doctor.😁

[Sunrisejoy in reply to Jsceltic67]

Looks like I will be right behind you with starting and blood work etc. Cardio signed off on it today. 👍

[Eucalyptus22]

I was on Acalabrutinib for 4 years and then started having joint and muscle pain so dropped to 1 tablet per day. Been on 1 tablet since September and so far no problems. My bloods are checked monthly now.

[Jsceltic67 in reply to Eucalyptus22]

Thanks for the reply,appreciate it as good to know how people are getting on with certain drugs,been just a week now been on them,just a slight headache sometimes, not bad.Thanks John.

[Jsceltic67 in reply to Jsceltic67]

Morning here in Spain,been on the tablets 2 weeks now,been ok,maybe a slight headache now and again just take a paracetamol, go to see doctor today,had blood test on Wednesday, good luck to you.Thanks John.