Experiences with Acalabrutinib | HealthUnlocked

96 public posts

Acalabrutinib Ventoclax

Acalabrutinib after 2 cycles today is the day I start my Ventoclax cycle.So far my results have been brilliant on Acalabrutinib I am hoping for the same on my new path on this second part of my trial I will still be taking Acalabrutinib dailyAcalabrutinib after 2 cycles today is the day I start my Ventoclax cycle.So far my results have been brilliant on Acalabrutinib I am hoping for the same on my new path on this second part of my trial I will still be taking Acalabrutinib daily

Yidarmy69in CLL Support

Off Ibrutinib .. on Acalabrutinib

bruising ( ignored ) all in all I am happy with the Acalabrutinib .... we shall see .bruising ( ignored ) all in all I am happy with the Acalabrutinib .... we shall see .

fish61in CLL Support

Dr Nicole Lamanna's Thoughts on the Recent FDA Approval of Acalabrutinib in CLL

Early phase I/II studies of acalabrutinib in CLL indeed suggested that this agent appears to have fewer adverse events than its predecessor.Early phase I/II studies of acalabrutinib in CLL indeed suggested that this agent appears to have fewer adverse events than its predecessor.

AussieNeilAdministratorin CLL Support

Ibrutnib vs Acalabrutinib

Treatment starting soon and given option on 2 drugs Ibrutinib and Acalabrutinib by my hematologist, if one had to choose for first frontline treatment which should it be?Treatment starting soon and given option on 2 drugs Ibrutinib and Acalabrutinib by my hematologist, if one had to choose for first frontline treatment which should it be?

Carl1987in CLL Support

Is it time to switch to acalabrutinib?

Should i try acalabrutinib?Should i try acalabrutinib?

suz02in CLL Support

A quick question before I forget it about ,,Acalabrutinib

Good morning I've been trying to learn about Acalabrutinib but having some problems finding much information ,,,,,,, and then deciphering it.Good morning I've been trying to learn about Acalabrutinib but having some problems finding much information ,,,,,,, and then deciphering it.

michaelmacin CLL Support

Follow up of post 2 months ago .leg pain .

Acalabrutinib is causing mouth sores ( I can live with ) rashes and severe itching ( controlled by very hot compresses and a 50 gallon drum of cortisone ) .. above side effects better than leg pain .....thanks again for everyone’s input Fish61Acalabrutinib is causing mouth sores ( I can live with ) rashes and severe itching ( controlled by very hot compresses and a 50 gallon drum of cortisone ) .. above side effects better than leg pain .....thanks again for everyone’s input Fish61

fish61in CLL Support

Please share experience of venetoclax plus obinutuzimab or acalabrutinib treatment in a survey that may help others gain access?

WE NEED YOUR HELP You may have seen and responded to this request for help in this survey lead by Canadian CLL groups, it was posted a while back by CLLPAG https://healthunlocked.com/cllsupport/posts/142434850/survey-for-cll-patients-having-taken-venetoclax-or-acalabrutinib IF YOU ARE IN THE UK OR INWE NEED YOUR HELP You may have seen and responded to this request for help in this survey lead by Canadian CLL groups, it was posted a while back by CLLPAG https://healthunlocked.com/cllsupport/posts/142434850/survey-for-cll-patients-having-taken-venetoclax-or-acalabrutinib IF YOU ARE IN THE UK OR IN

HAIRBEAR_UKAdministratorin CLL Support

Final BMB on AVO Trial Tomorrow

If my last node is down by 1mm over my last staging, then I’ll get to decide about staying on the Acalabrutinib and Venetoclax or stopping them both. My current leaning is toward coming off. Thoughts? GlennIf my last node is down by 1mm over my last staging, then I’ll get to decide about staying on the Acalabrutinib and Venetoclax or stopping them both. My current leaning is toward coming off. Thoughts? Glenn

Lily_Pad_Masterin CLL Support

Acalabrutinib Achieved Breakthrough Designation for CLL

This now fast-tracks Acalabrutinib (Calquance) for full FDA approval. https://www.onclive.com/web-exclusives/fda-grants-acalabrutinib-breakthrough-designation-for-cll?eKey=Z2xlbm5vdGZAZ21haWwuY29t&%20kxplacementid=enlThis now fast-tracks Acalabrutinib (Calquance) for full FDA approval. https://www.onclive.com/web-exclusives/fda-grants-acalabrutinib-breakthrough-designation-for-cll?eKey=Z2xlbm5vdGZAZ21haWwuY29t&%20kxplacementid=enl

Lily_Pad_Masterin CLL Support

SKIP VENETOCLAX, GO TO ACALABRUTINIB

My CLL specialist said when I need treatment again (had to quit Ibrutinib after 3 years due to afib), he would probably start me on Acalabrutinib. My oncologist/hematologist indicated the treatment would be Venetoclax. I see the specialist on a consultation basis. Anyone face this situation?My CLL specialist said when I need treatment again (had to quit Ibrutinib after 3 years due to afib), he would probably start me on Acalabrutinib. My oncologist/hematologist indicated the treatment would be Venetoclax. I see the specialist on a consultation basis. Anyone face this situation?

cll2013in CLL Support

Stopping Ibrutinib

Aussie Neil suggested Acalabrutinib and my Oncologist agreed ....Aussie Neil suggested Acalabrutinib and my Oncologist agreed ....

fish61in CLL Support

So Much Money in the Drawer

after all of this I find myself with a half sleeve of Ibrutinib and a full sleeve of the same, value about $17k and 3 weeks worth of Acalabrutinib worth about $9k in my drawer.after all of this I find myself with a half sleeve of Ibrutinib and a full sleeve of the same, value about $17k and 3 weeks worth of Acalabrutinib worth about $9k in my drawer.

KevinCLLITPin CLL Support

Survey for CLL patients having taken Venetoclax or Acalabrutinib

CLL/SLL Patient Survey If you have CLL or SLL and have been treated with the following therapies, you can help by completing our survey: Venetoclax (Venclexta) + obinutuzumab (Gazyva) for first-line treatment of CLL/SLL Acalabrutinib (Calquence) with or without obinutuzumab (Gazyva) for first-lineCLL/SLL Patient Survey If you have CLL or SLL and have been treated with the following therapies, you can help by completing our survey: Venetoclax (Venclexta) + obinutuzumab (Gazyva) for first-line treatment of CLL/SLL Acalabrutinib (Calquence) with or without obinutuzumab (Gazyva) for first-line

cllpag_canadain CLL Support

Ace -311-CL-311 UK

Hi I’ve just been randomised on Ace trial 311 and have been given arm A which constantly of Acalabrutinib 100mg daily then Venetoclax starting on 20mg on cycle 3 for 1 week then 50mg for a week then 100mg then 200mg then 400mg daily I’m in uk really excited but also very nervous as this is my firstHi I’ve just been randomised on Ace trial 311 and have been given arm A which constantly of Acalabrutinib 100mg daily then Venetoclax starting on 20mg on cycle 3 for 1 week then 50mg for a week then 100mg then 200mg then 400mg daily I’m in uk really excited but also very nervous as this is my first

Yidarmy69in CLL Support

Remission on Acalabrutinib and Venetoclax

Hi everyone I’ve been on Ace cll 311 trial for 3 1/2 months after my latest CT scan my Dr has told me I am in remission I have to keep taking both tablets to get to a deeper remission I feel very lucky and privileged to be a part of this wonderful trialHi everyone I’ve been on Ace cll 311 trial for 3 1/2 months after my latest CT scan my Dr has told me I am in remission I have to keep taking both tablets to get to a deeper remission I feel very lucky and privileged to be a part of this wonderful trial

Yidarmy69in CLL Support

To start treatment or not? Please.

Based on an extremely large spleen (he cannot even feel the spleen) he said it is time to start Acalabrutinib. Your thoughts, please. My enlarged spleen (was at 19 a year ago) and my neck lymph nodes do not bother me.Based on an extremely large spleen (he cannot even feel the spleen) he said it is time to start Acalabrutinib. Your thoughts, please. My enlarged spleen (was at 19 a year ago) and my neck lymph nodes do not bother me.

bayside64in CLL Support

Phase 2 study of acalabrutinib in ibrutinib intolerant patients with relapsed/refractory CLL

At a median follow-up of 19 mo (range 1-31), 67% of pts remained on acalabrutinib.At a median follow-up of 19 mo (range 1-31), 67% of pts remained on acalabrutinib.

Jm954Administratorin CLL Support

Anyone taking 100 mg of acalabrutinib?

I switched from acalabrutinib to venetoclax. Now I plan to take both. I want to only take 100 mg of acalabrutinib to minimize side effects. Is anyone doing well on that dosage?I switched from acalabrutinib to venetoclax. Now I plan to take both. I want to only take 100 mg of acalabrutinib to minimize side effects. Is anyone doing well on that dosage?

profrichin CLL Support

ACE CLL- 311 Update Acalabrutinib Venetaclax

Hi everyone I’ve been on this trial since October . I had a CTt scan last week got the results today all of my noades are now normal size bloods all good the best news is I’m in remission got to carry on taking the tablets to hopefully get a deeper remission .I will have a BMB in a few months to seeHi everyone I’ve been on this trial since October . I had a CTt scan last week got the results today all of my noades are now normal size bloods all good the best news is I’m in remission got to carry on taking the tablets to hopefully get a deeper remission .I will have a BMB in a few months to see

Yidarmy69in CLL Support

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