DawnR, Having CLL and being on imbruvica treatment should not interfere with getting a tetanus shot, because in the US, live cellular tetanus vaccines are no longer permitted. IE, the vaccine will not be harmful. However, having CLL and being on imbruvica may well dampen your response to vaccination.
Because you are immunocompromised, if you get a deep wound, your doctor may well recommend an injection of Tetanus Immune Globulin along with a Tetanus shot.
I keep current with my tetanus boosters and my having CLL plus being very active outside as a geologist makes it doubly important. I have had no reactions to the booster other than a very sore arm for a day. Agree with gardening-girl.
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