This is the second time I have had CLL... I had it 9 years ago, and after a cocktail of infusion chemo with Rituxin and 2 other drugs....I went into remission until 4 months ago. I have been treated with Imbruvica daily and have taken it for 3 months ... As I understand.....when the results come in from my new Bone Marrow Aspiration come in, and the Imbruvica is working, I will continue to take it indefinitely as long as it is showing success. I am not sure how I feel about continuing a medication that causes some unpleasant side effects for an undetermined amount of time just because it works.... Do I, as a patient, have the option to request chemo via infusion...and take it for a course of treatment and see if the chemo was successful (as in my first round of chemo)....and determine I am in remission, and stop the course of chemo.... Does this make sense?