Cyclophosphamide for the elderly: My elderly... - CLL Support

CLL Support

23,253 members39,949 posts

Cyclophosphamide for the elderly

nigeldodd profile image
1 Reply

My elderly mother was recently diagnosed with CLL. At that time (beginning April 2016) the associated acute condition was haemolysis which had already reduced her red blood count to the mid 40s. She was given transfusions and steroids. She responded well and was later discharged and the dose of steroids reduced while monitoring her bloods. Her lymphocyte count is now down around 5 having been over 100.

Unfortunately she was susceptible to infection and was readmitted twice with respiratory tract infections.

She was going to be infused with low dose Rituximab but this has been changed to Cyclophosphamide (50-100mg) orally with an anti-sickness drug while continuing to reduce the steroid dose. Although she is 95 she has had no serious health issues until now.

I would appreciate the views of this community on this line of treatment.

Written by
nigeldodd profile image
nigeldodd
To view profiles and participate in discussions please or .
Read more about...
1 Reply
Cllcanada profile image
CllcanadaTop Poster CURE Hero

Hi

Usually chlorambucil is used in the patient with advanced age or comorbidities. It is the same family of chemotherapy and is an oral treatment... both have been used for over 50 years...

~chris

Not what you're looking for?

You may also like...

Ibrutinib and increased white count

My aunt is on her fourth dose of ibrutinib. Her white count went from 33000 to 114000. She was told...
Marisa50 profile image

5 months on Ibrutinib with side effects

My mum started Ibrutinb and seemed to be getting on OK for a while. She recently had palpitations...
mouseygirl profile image

3rd or booster

I am chasing up my status regarding 3rd + booster or just 2 + booster. I had 2 AZ early 2022 and a...
Belfastbees profile image

Venetoclax - hallucinations?

Hello all, First post here. I'm posting on behalf of my mom. She is 66 and has had CLL for...

Negative IgG antibodies from 1st shot of Pfizer’s Covid Vaccine

My twin sister has CLL and we finally got the results today from Boston Heart Lab’s semi...
Twin21 profile image

Moderation team

See all
Newdawn profile image
NewdawnAdministrator
Jm954 profile image
Jm954Administrator
AussieNeil profile image
AussieNeilAdministrator

Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.

Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.