Changed from duloxtine to Amitriptyline

[Anaensan]

I was on duloxtine for 2 months, I felt better only first week , then 5 weeks things became not well .My doctor has advised me to chane to amitriptyline, I did that for 6 days now , today I feel my head muscles so tight and I feel impulsive and cant sleep

[Agora1]

Hi Anaensan, Welcome to a great community.

Amitriptyline is an older but proven drug in helping patients with pain control etc

I was prescribed it at one time for Fibromyalgia. Wasn't on it long, can't remember why.

Unfortunately, there isn't one drug that fits all. It's basically a trial and error experience

in finding the right drug, the right dosage with the least amount of side effects.

Don't give up, contact your prescribing physician and let him/her make the decision

in what to do next. Afterall, they know your health history. Good luck in finding what

works best for you and you alone xx

[Ryanlion]

Could you be still having withdrawal from duloxotine, i would check withdrawal symptoms list because i know they are ugly even after short usage. I prefer the older tricyclic drugs like amitriptyline or clomipramine etc.. In my opinion they are much better than these modern drugs,once you get passed the side effects. I was on clomipramine for 15 years it was brilliant, until it stopped working for me & my body wouldnt accept a higher dose. Now i am on venlafaxine, similar to duloxotine and i hate it but i cant seem to take anything else. Venlafaxine has horredous side effects for me even though i have been on it 2 years. Hoping therapy is the key to freedom from them. I would check with your Dr and give Amitripyline a chance, they can take upto 5 weeks to work if he thinks it is best. Hope this helps.