I've been feeling worse lately, more anxiety and depression. I take gabapentin for anxiety and that has helped a lot vs where I was a few months ago. My new doctor prescribed Trintellix for depression and this is the third antidepressant I've tried. I started feeling better at first with 5mg, now it's been 2 weeks at 10mg and my mood has been very up and down. The anxiety is worse as well. My doctor said I need to give it several weeks to reach full effect.
Today was really hard. I try to tell myself this is only temporary and I will get better but it's been almost 10 months and I'm really tired. It's so hard to keep going. Any encouragement from those who have come through the other side would be appreciated!
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RMHiker
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I'm back on the other side, again! Many years ago when I was first diagnosed it took a couple of cocktails of meds before we found the right one. It was horrible because there is actual physical illness that goes with all of this. I'm 5 ft 10 went from a healthy size 12 to a size 8 in a matter if weeks. So I feel you.After a month or so on my new meds I started feeling pretty good. I was able to learn some techniques to calm myself and different ways to think about things. My biggest help I found was journaling. When I made it to the other side, I was strong enough to successfully run a a 10 million dollar company!
I have to say I've slipped back to the wrong side twice since then. But each time was shorter because I pulled out my tools I've learned. You will too! You're here asking for support and that's the biggest step you can take! You've got this!
Thank you for the encouragement. Especially hearing that you were able to get well enough again to run a company, wow! I'm an engineer and I wonder when my mind will ever be that sharp again, so your story gives me hope. Thank you very much!
I completely understand how you're feeling because I’ve struggled with anxiety and depression too. I’ve been through several antidepressants, and I know how discouraging it can be when things seem to work at first, only to feel like you’re backtracking. When I tried Trintellix, I had a very similar experience—it took time, but after a few weeks, things leveled out, and I began to feel much more stable and less overwhelmed by anxiety. On a friend's recommendation, I ordered it from this pharmacy - world-delivery-service.com/..., the order arrived quickly, and the medication worked as it should.
It’s such a frustrating process, but your doctor is right: it often takes several weeks for the full effects to kick in. One thing that helped me was keeping a journal to track my mood. It let me see small improvements over time, even when I didn’t feel them day to day. I also leaned into routines—regular sleep, light exercise, and time outdoors—even if they felt hard. It’s okay to feel tired and frustrated, but remind yourself that you’re doing the best you can right now. This rough patch doesn’t mean the medication isn’t working; it’s just part of the adjustment. You’ve made it 10 months fighting this—it shows your strength, even if it doesn’t feel like it right now.
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