Feel desperate and feelings of despai... - Anxiety and Depre...

Anxiety and Depression Support

92,982 members86,850 posts

Feel desperate and feelings of despair on sertraline plz help

Donna67honey profile image
17 Replies

Hi I have anxiety and depression and recently came off citalopram after 7 months on them, they were working for a good 3 month and then just didn’t do much for me anymore even at 40mg, I have now went back onto sertraline which I was taking before citalopram, I’m 2 weeks into 50mg and I feel absolutely dreadful, every few mins I get this sinking feeling like I’m descending into a pit of despair and then it lifts again and so on and this is happening all throughout the day and my mood is flat because of this I am really worried why this is happening. I’m scared to try any more antidepressants as haven’t had much luck with ssris. Can anyone help? Is this normal restarting sertraline? Sometimes think what’s the point?

Written by
Donna67honey profile image
Donna67honey
To view profiles and participate in discussions please or .
Read more about...
17 Replies
pink83737 profile image
pink83737

Hi I’m on sertaline also and the meds do take some time to kick in and to actually start working. When you first ever took sertaline did you have the same feeling?

Donna67honey profile image
Donna67honey in reply topink83737

Thank you for your reply, yes I did actually when I think about it, it was as if I was a zombie for a couple of weeks, this time it feels like I’m ok one minute and then I get these waves of impending doom and despair which then lifts and then I’m ok and starts again and so on, it’s quite frightening, I’m just wondering if 50mg is enough to start.

pink83737 profile image
pink83737 in reply toDonna67honey

Yeah that’s enough to start I wouldn’t recommend jumping up to 100-200mg when first starting this medicine you have to slowly increase it. But your feelings are normal :) take deep breaths you aren’t alone I know what it’s like.

Donna67honey profile image
Donna67honey in reply topink83737

Thanks so much it’s an awful feeling 😊

pink83737 profile image
pink83737 in reply toDonna67honey

I agree

Crochetbaby profile image
Crochetbaby in reply toDonna67honey

Hi can I ask how you feel on the sertraline now. I’m two weeks in and feel dreadful.

Donna67honey profile image
Donna67honey in reply toCrochetbaby

Still get those feelings and I’m going to come off it in 2 weeks and try something else as I feel flat like nothing excites me anymore!

Crochetbaby profile image
Crochetbaby in reply toDonna67honey

Yes I feel dreadful I thought I would give it 4 weeks. I feel so weak. Constant diorrhea crying and more anxious than before.

Donna67honey profile image
Donna67honey in reply toCrochetbaby

Takes a good 8 weeks to get in your system as well if your not happy with it I would definitely go back to the doctors, citalopram is really good for anxiety and depression that was my favourite but it stopped working for me I was gutted

Donna67honey profile image
Donna67honey in reply toDonna67honey

I’m not very happy on sertraline but il have to wait until after new year to see the doctor now il never get an appointment, there’s lots of others to try

Crochetbaby profile image
Crochetbaby in reply toDonna67honey

It’s just such a horrible struggle everyday.

Donna67honey profile image
Donna67honey in reply toCrochetbaby

It is it’s awful u just gotta keep going until u find something that works

Crochetbaby profile image
Crochetbaby in reply toDonna67honey

Thank you.

RoseFleur profile image
RoseFleur

One of the medicines (could have been sertreline) also gave me those waves of feelings. I had to get off it, and am now on two others. Good luck to you!

Donna67honey profile image
Donna67honey in reply toRoseFleur

Which ones are you on now if you don’t mind me asking? I feel flat on sertraline and dull all the time

RoseFleur profile image
RoseFleur in reply toDonna67honey

Citalopram (Celexa) and Buproprion

melantha profile image
melantha

Yup. I am on sertraline and I did NOT do well in it to start. I got super depressed to the point of even having to leave work early. It lasted sort of on and off for the first few weeks, but then my body seemed to adjust to it. My depression went back to base levels and the sertraline seems to help my anxiety a bit, so I’ve stuck with it. Hopefully it works out for you too.

Not what you're looking for?

You may also like...

Help with feelings of despair/panic

Hey everyone,I had a bad (what I can only describe) as a panic episode yesterday. I felt like I was...
Pheebs93 profile image

Good and bad days on sertraline?

I’m on day 17 of sertraline and I feel so down, 2 days ago I felt so happy as I felt my head was...
Notebook30 profile image

feel so anxious on 25 mg sertraline

hi x l have been on 25mg sertraline for 36 days and l am feeling very anxious and shaky at times....
RayannAbbey profile image

Anti depressants sides effects

I recently came of hrt as I didn’t feel it was helping me apart from my mid month dip. My anxiety...

Meds Are Making Me More Depressed.

Clearly I wasn’t doing great before getting started on the meds my psychiatrist prescribed me, but...
JDGarza profile image

Moderation team

Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.

Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.