A clinical trial of the cancer drug bexarotene showed that it repaired the protective myelin sheaths in Multiple Sclerosis patients.
The drug had some serious side-effects, from thyroid disease to raised levels of fats in the blood, which can lead to dangerous inflammation of the pancreas. But brain scans revealed that neurons had regrown their myelin sheaths.
So, that's that one ruled out.
There is a new trial up this year, This trial will monitor the effects of the diabetes drug metformin along with clemastine, an OTC antihistamine. They've both been shown to (safely???) promote remyelination, makes sense to try both together if so.
Interesting. Min-102 is a derivative of several metabolites of pioglitazone, an anti diabetic drug. Here's a look: minoryx.com/leriglitazone/
Also of note, is the approval of a study in the EU involving male pediatric patients with first evidence of cerebral lesions: minoryx.com/leriglitazone/
It is worth a shot, and I've thought about giving it a go on more than one occasion. Beware, I was speaking to a friend (who happens to be a doctor), as far as he was concerned, these drugs lower your blood sugar.
He ran through a list of horrifying outcomes from having persistently low blood sugar levels. Top of my head, I cannot recall. That sort f info, you need to take notes.
Then again, Ozempic is prescribed for Diabetes, and similarly lowers your blood sugar. Now it's a weight-loss drug you simply have to ask for.
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Gene Therapy and remyelination as a cure
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