Man's Prostate Cancer Caused "Uncontrollable" Irish Accent, Doctors Say

[cesces]

HEY, someone has to post the important papers.

Man's Cancer Caused "Uncontrollable" Irish Accent, Doctors Https://futurism.com/neoscope/cancer-irish-accent

In a truly bizarre case, doctors have documented for the first time a man who appears to have developed a random Irish accent after getting prostate cancer — a disease that eventually killed him.

As a recent paper in the journal BMJ Case Reports, the man in question was in his 50s when he was diagnosed with prostate cancer.

Foreign accent syndrome as a heralding manifestation of transformation to small cell neuroendocrine prostate cancer

orcid.org/0000-0002-6925-30... Broderick1, Matthew K Labriola2, Neal Shore3 and orcid.org/0000-0001-7012-17... J Armstrong4

Correspondence to Dr Amanda Broderick; [e-mail]; Dr Andrew J Armstrong; [e-mail]

Abstract

A man in his 50s with metastatic hormone-sensitive prostate cancer, receiving androgen deprivation therapy and abiraterone acetate/prednisone, presented with an uncontrollable ‘Irish brogue’ accent despite no Irish background, consistent with foreign accent syndrome (FAS).

He had no neurological examination abnormalities, psychiatric history or MRI of the brain abnormalities at symptom onset. Imaging revealed progression of his prostate cancer, despite undetectable prostate-specific antigen levels.

Biopsy confirmed transformation to small cell neuroendocrine prostate cancer (NEPC).

Despite chemotherapy, his NEPC progressed resulting in multifocal brain metastases and a likely paraneoplastic ascending paralysis leading to his death.

We report FAS as the presenting manifestation of transformation to small cell NEPC, a previously undescribed phenomenon.

His presentation was most consistent with an underlying paraneoplastic neurological disorder (PND), despite a negative serum paraneoplastic panel. This report enhances the minimal existing literature on FAS and PNDs associated with transformed NEPC.

dx.doi.org/10.1136/bcr-2022...

[kainasar]

Take him directly to the Pub - recommended SOC therapy.

[Kaliber in reply to kainasar]

lol

[Kaliber]

I “ get it “ …. Happens every time I use Irish Spring bar soap too , lad-ies.

Just say’in

😁😁😁

[Kaliber]

I’ve developed a noticeable “ slur “ in my speech, heavy at times. Medical staff thinks its small vessel white matter damage due to long term Xtandi ( which crosses the blood brain barrier. ) use. A recent brain xray shows it. It’s quite mild they say ( wtf ? ) …. I could see how a patient with a heavy southern accent…and …Xtandi crossover slur might sound Irish . Seems like a long shot it being Irish to , just say’in.

[Hidden]

poor Bloke!

[dhccpa]

There are SOC treatments to deal with that. They're brutal on side effects, though.

[MateoBeach]

Or in a Scottish accent; “I’m not a miracle worker, Captain, I’m just a mere country doctor”.🤷‍♂️

[MateoBeach in reply to MateoBeach]

Now hand me that tri-corder. No, the medical tri-corder.

[Hidden in reply to MateoBeach]

I used to man the control system during gas turbine engine tests. We all wore headsets with earphones and mics. "I canna give ya any more captain, she's gonna blow" was always worth a giggle.

[maggiedrum]

Like many other topics, I am an interested amateur in linguistics. Accents can be mimicked by many people but what I have noted is that this is an intentional effort that is only successful when the producer of the accent has an exceptional "ear" for the nuances of the accent (or language in general) and is motivated to cause his/her vocal cords, breath, mouth and tongue positions, and other physical/physiological necessities to accomplish a reasonably accurate "accent". I have a healthy skepticism of this being caused by something that is not intentional, in addition to the development of exceptional intentional control of a very complicated process. Some are born with the ability to pick up languages and accents after they are in the usual formative years of brain development and early practice with frequent situations where they can hear the language/accent.

I am a skeptic that they have actually identified and definitely associated the cancer with the accent. Stranger things have happened though. I am one who has an exceedingly (and disappointing) inability to even come close to learning a new language or accent despite years of motivation and practice. The case presented would border on a miracle situation. Creating a double blind trial to confirm it would also need a miracle.

I was born a skeptic though. And I know too much about how little even less complicated mechanisms defy understanding of the brain. For instance, why does low testosterone cause depression. Or, anything else where the exact mechanism to cause depression has been identified and proven. And there is a larger population of those with depression than there are those who have suddenly developed accents.

[j-o-h-n]

It wasn't the Pca that did him in-..... it was his mistake of singing Oh Danny Boy, in Conner's pub and wearing an orange boutonnière on St. Patrick's day.....

Good Luck, Good Health and Good Humor.

j-o-h-n Thursday 02/16/2023 2:25 PM EST