Would love to get your input into potential options for my Dad.
We’re at the point we need try something new now.
So we have done triple hormone therapy Bicalutamide (which we stopped a few years back) Degarelix and Zytiga are also not suppressing a PSA rise now which is currently 61. It has been as high as 433 about 9 years ago. We got several years out of the above. He is still asymptomatic. Options I see moving forward.
* Enzalutamide (Xtandi)
* High dose Testosterone to shock the PCa cells. (I understand this would have to be under close supervision / monitoring)
* Low Dose Chemo with Cabergoline
* Lu-177 or AC-225 (My Dad’s PSMA scan was PSMA positive)
Thoughts on the above and potential sequencing etc, and the prospect of certain agents re-sensitising older agents we have used such as Zytiga.
We shall of course be conversing with my Dad’s prostate oncologist but it would be nice to get some input from you guys
Thoughts on the above and potential sequencing etc would be great.
Thanks in advance.