Hi Everyone ive been a member for a cpouple of years but havent posted much. I was Diagnosed with a PSA of 5000 and a gleason 9. Ive only had ADT which worked really well for 18 mnths . Im about to start some leutetium 177 psma therapy here in australia and wondered what people thought about combining it with zytiga or xtandi. Im now on xgeva. Ive used lots of natural supps, juice,meditation etc but my PSA is around 120 now and I have mets. Just wanting thoughts. I wasnt offered chemo at the start of all this. The leu177 has the least side effects and has been effective in Germany. Recently Ive been getting very tired and some bone pain, but im still working and working. thankyou in advance.