Anyone here diagnosed with secondary cancer after chemo and radiation for prostate cancer?

[Dachshundlove]

I’ve been reading lately about secondary cancers associated with chemotherapy (platinum more often than taxane) and radiation treatment for solid tumors such as prostate cancer. We are dealing with a very resistant type of prostate cancer and as a result, my husband has had carboplatin, docetaxel, Lupron, Zytiga, and consolidating radiation all within 16 months. I’m now wondering about secondary cancers associated with the aforementioned treatments. Thoughts and experience much appreciated.

[Tall_Allen]

I think that's the least of your worries. It takes upwards of 10 years for radiation-induced secondary cancers to develop, and even then, the incidence is low.

prostatecancer.news/2016/08...

[Hidden]

As one doctor said, "You have to deal with the cancer you have now, not the cancer you might have later."

Unfortunately, we find ourselves in the position of evaluating the threats to our lives in terms of how immediate they are. Whatever is going to get us first has priority.

[LearnAll]

It is a very logical worry. Heavy cancer treatments do increase risk for other cancers and the right thing to do is to stay alert about this possibility and do surveillance for these other possible cancers.

There are biomarker who can indicate if something else is cooking and is in early stage.

Some simpler biomarkers are:

Carcino-Embronic Antigen (CEA)...for Colon Cancer

Alpha Feto Protein ( AFP)...for Liver cancer

CX Bladder ...for Urinary bladder cancer

Peripheral Blood Smear ...For Leukemias.

These are not 100% specific but can give us an early clue of brewing cancers.

[scarlino]

It is possible the cancer mutates to small cell type. That has occurred for me. Has any genetic testing been done? There are a number of clinical trials ongoing. Immunotherapy using Olaparib and Keytruda is the one I’m currently on but you need to have a genetic mutation that fits the criteria. Something to consider.

[Patrick-Turner]

I was diagnosed in 2009, Gleason 9, inoperable, at age 62. I have had many treatments, presently with another round of Lu177, after having 4 shots last year.

7 weeks ago I had FDG PET scan that did not reveal any any Pca that did not generate PsMa, so no doctors have told me I have more than one type of Pca or any other cancer type to deal with.

Tall Allen is probably right about treatment caused cancers.

Maybe you need to focus on what the immediate threats are to health, not the imagined threats of the future.

Try to look on the bright side,

Patrick Turner.

[EdBar]

I was diagnosed with melanoma about a year after being diagnosed with prostate cancer but it was far more likely due to a genetic mutation that I have and time spent enjoying outdoor sports than the chemo and radiation treatment I received.

Ed

[mcp1941]

Like Tall Allen said, it will take many years for a secondary cancer to show after radiation. I was DXd last year with Multiple Myeloma 22 years after radiation for PCa. The problem with secondary cancers is pinpointing the cause. Was it the radiation or was it something else

MikeP

[Bethpage]

12 months after having 7 sensitive scans to find the recurrence in the prostate bed, then 39 EBRT for that, my husband was diagnosed with chronic lymphocytic leukemia. It's aggressive. His bloodwork prior to the first five of the sensitive scans was perfect, but at diagnosis of CLL, it was found that he has 98% deletion of the 13Q chromosome and 33% deletion of the 11Q chromosome. I read and participated in a conversation regarding bone- and blood-related cancers secondary to radiation received for treatment off PCa in this forum about two weeks ago.

[j-o-h-n]

Like EdBar's post above, I too have developed a melanoma which metastasized in my Lungs. It is being treated with Keytruda and apparently the Keytruda is working.

The relationship between my Pca and my Melanoma is because God doesn't like me.

Good Luck, Good Health and Good Humor.

j-o-h-n Monday 10/12/2020 5:14 PM DST

[Vitaminlover]

Yes, my husband developed a malignant bladder nodule 9 months after pelvic radiation. We were also told that a connection so quickly would be unlikely.