Yesterday was my first round of treatments for a new clinical trial that involves an infusion of a novel platinum based chemotherapy drug currently named PT-112 followed by the immunotherapy drug avelumab.
I had two IV’s placed. One was for the infusions and the other was for blood draws. I started at 0700 and ended at 1600. Zofran (ondansetron) was given 30 minutes before PT-112 then PT-112 over one hour. Serum levels of PT-112 were checked every 2 hours.
Next I was given 650 mg of acetaminophen orally and 50 mg of diphenhydramine (Benadryl) IV which I hate the way that feels. Avelumab was infused 30 minutes later over an hour.
I felt no side effects during the PT-112 infusion and a very small amount of itching during the avelumab infusion.
On a side note I decided on my own to water fast for 2.5 days before the infusions and 1 day after for a total of 85 hours.
I broke out in a fever at around 6 pm last night with body aches and just went to bed. Not feeling my best this morning but hoping that breaking my fast will help.