Provenge: Finished second infusion... - Advanced Prostate...

Advanced Prostate Cancer

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Provenge

hysir profile image
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Finished second infusion. Side effects were similar to first infusion , but didn't last as long. I was walking around during the process and felt pretty good. During my 30 minute observation I got chills, dizziness, and nausea. Also , I was very fatigued, more so than first infusion. Blood pressure dropped to 90/50. I was released in approx. 2 1/2 hours. got home and went straight to bed. Woke up in about 2 hours feeling better. Drank fluids and had soup. Checked blood pressure that night 137/80. Felt okay the next morning. On the day of infusion, I ate breakfast at 530a, started infusion at about 9am and finished around 1030a. Nothing to eat until that night. I went a long time without food and maybe that caused severe fatigue. One more to go and I will be done.

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hysir profile image
hysir
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16 Replies

Glad to hear that all in all, it's going well. Two down, one to go. Piece of cake!

Roland632017 profile image
Roland632017

Hi hydro

I noticed you said you are 7 years survivor of PCa. Since such a long time. This morning I implore about cancer basics. You think you are able to point out anything about cancer cells at cellular level. I done some reading and the information I gathered said cancer cell has killer microbes as well as very good as disguise. Hence treatment has been difficult as the body immune system cannot differentiate them from normal cells hence the aggressive proliferation and invasions till we die. Your comments please.

Roland632017 profile image
Roland632017 in reply to Roland632017

Sorry about the name as the word system got it wrong. My apology hysir

hysir profile image
hysir in reply to Roland632017

i found an article on immunotherapy that might be helpful, go to verywell.com and search for immunotherapy 101.

Roland632017 profile image
Roland632017 in reply to hysir

Hi Hyatt

Thanks for directing me the immunology website. It going to take some time to digest. Research on inflammation, acquired immunity, cell meditated immunity and humoral immunity is really interesting. If only we can have the correct WBC recognised the unwanted cancer cells then the healing process is the ultimate goal.

Thanks again

Roland632017 profile image
Roland632017 in reply to Roland632017

Sorry about the name hysir

Roland632017 profile image
Roland632017 in reply to Roland632017

Hi hysir

Just a thought. If you can manage to transform some of the WBC to Le killers of bacteria, fungi or unwanted antigen like through mind power and positive thoughts your body immune system can actually fight this foreign invasion even without drugs. Just a thought. In future it might happen.

hysir profile image
hysir in reply to Roland632017

you are welcome

Muldoon432 profile image
Muldoon432

My second infusion was the worst. Chills, fever, fatigue. Last one was somewhere between the first and second.

DenDoc profile image
DenDoc in reply to Muldoon432

My second one was awful with extreme chills ("rigors") and fatigue. Treated with IV Benadryl which made me very tired. I am doing my third round next week. Did they do anything different for you during your third infusion? I would like to avoid a repeat.

hysir profile image
hysir in reply to DenDoc

Just finished 2nd infusion. It went better than the first, timewise to recover from chills, fatigue, and nausea. We will get thru the third infusion. Stay strong.

Muldoon432 profile image
Muldoon432 in reply to DenDoc

They just watched me closer. I had the same symptoms as you did on the second infusion but not until I got home. The third and final one they watched me longer. They already were giving me Benadryl. I felt flu symptoms when I got home but not nearly as severe as before. I slept almost as soon as I got home and spent most of the next day in bed too, but then I was ok. That second infusion was a shock though since I had no symptoms for the first. Part of me was happy though - knowing the therapy was doing something. Weird, but if you have to have your oil changed for three hours three times you kind of want to have some confirmation it is doing something. Good luck!

Olivia007 profile image
Olivia007

Glad to hear ur doing well.

hysir profile image
hysir in reply to Olivia007

1 more to go

Shepard profile image
Shepard

I had no reaction to infusions - took one Benadryl instead of two. My problems were with the collection. I reacted to the anti-coagulant and was sensitive to the amount of pressure in the flow process. I found that when the med tech carefully monitors the pressure flow I did much better. Other times I was eating "tums" by the handful to ward of nausea. Also found it beneficial to eat a high calorie meal before collection. I am now nearly five weeks since the last infusion and am anxious to learn how much the PSA rose from the starting point of 4.31. Expect a new mix of meds, but was told that I would continue on Casodex and change the Lupron interval from six months to three months. AT this point, I have no opinion as to the benefit of the Provenge treatment. I have been active on the ranch (as I was before) and getting some good work projects finished before the new meds. End of year blessings to ALL!

sidnw profile image
sidnw

I had my 3rd provenge trtmt. about 2-1/2 wks. ago..I have beenextremely fatigued...feel

sickly and my walking is bad. I was feeling better before trtmt. I'm probably much older than most of you but have had prostate cancer quite a while with no serious consequences until 2017. Right now after provenge I have No Appetite whatsoever. My wife Shyrlene has tried everythg. to eat and it makes me nausous. I have had 2 Procrit shots recently..so far no change. I have talked to Joel Nowak who has given me suggestions. One..get a second opinion which I just made the appointmt. with..end of mth. Joel is so intelligent and knows so much....and so patient ....Shyrlene keeps talking about him to our frds. She said she didn't know there were people like him around...I hope I can be around for awhile..life is certainly worth fighting for as you all know. wish me luck!

sidnw

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