My Dad is going to be screened for the Veru-111 trial soon. I’ve been looking all over the internet trying to find others that may have gone through this trial. I understand it’s new, but I’m just looking for feedback on what others may know. I’ve read the handout from the hospital and a couple of sites online that just give a description. My Dad’s oncologist seemed excited about this treatment. It seems promising.
My dad (76) has been on this journey with stage 4 metastasized prostate cancer for a little over a year now. He has exhausted the majority of treatments. Does that mean this treatment-veru is a last resort? I’ve been so nervous and scared. He has castration-resistant prostate cancer with progression despite abiraterone, enzalutamide, and docetaxel chemotherapy. About 4 months ago, he began treatment with radium-223, and has received 5 of 6 infusions thus far. His oncologist does not feel he needs to complete the 6th. His alkaline phosphate were about 1500 prior to the start and now they are almost normal. However his PSA remains around 400.My Dad has the somatic TP53 mutation. He recently came down with a bad case of shingles and is having trouble getting rid of them despite medications. They are causing him terrible pain.
My Dad is being treated at Hopkins. They are going to be completing new scans as part of the trial. He does not have any organ involvement based on his last scan. I would love to know what treatments have been successful when most treatments have failed. It seems like he gets a good run for a few months and then they begin to fail. I would like to add that my dad continues to work despite all of these treatments. He is a true fighter! Also, what treatments have others found successful that have the P53 mutation? We would appreciate any advice or feedback as we plan the next step. Thanks so much!
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