Good morning,
I'm needing advice for my 82 year old dad. Dad has been fighting prostate for eight years. Upon diagnosis his PSA was 257 and he had a single lymph node found to be involved. He had chemo and started on lupron + bicalumatide. In 2020 the medicine began to fail and he had provenge and started on Xtandi. Now his Xtandi is failing. His PSA is presently 2.54, up from 1.17 three months ago.. which was about half of that the months prior.
To complicate things, in September 2021 he had to have a quadruple bypass which was complicated by AFib and the necessary medications for that (which he is still on).
Then in November 2021, he was diagnosed with a rare form of lymphoma in his brain. He went through a very difficult and rigorous chemo which demanded he stay in the hospital for two weeks at a time for each round. Fortunately, the chemo was very effective and he is about to celebrate 1.5 years in remission from the brain cancer. He is on no medication for this cancer presently.
Despite his age and his health battles, dad is far from a frail elderly man. He still preaches every Sunday at his church and leads Bible studies mid week. He says he feels fantastic! He has told me that he isn't ready to quit fighting.. he just doesn't want to have any more hospital admissions for treatments (like he had with the brain cancer).
Looking ahead to next steps, from what I understand pluvicto or another form of chemo is ahead. Is there anything else? And, between pluvicto and chemo, my assumption is that pluvicto will be more easily tolerated?
I've read that pluvicto is only affective about 30% of the time. How much more affective would chemo be and would the side effects be worth the pay out?
And if he were to decline either of these treatments, are there any other medications he could try?
I appreciate any help you could offer!
Lynsi