Hi all, I'm looking for some help staying positive. My Dad (62)is currently on the Peace 3 trial, he had 6 rounds of Xofigo finsihed December 22nd, he's on xtandi and zometa. His hemoglobin levels keep dropping despite infusions, today's reading 7.1, psa up to 170. His last scans -(CT and Bone scan) in Jan showed stable disease (widespread mets) nó organ involvement . Next 2 scans due on March 3rd.
Genetic testing done (saliva) no Brca mutation etc
I spoke to the trial nurse today as there was a mix up in his psa, she said the scan in March will determine what happens next. That his numbers aren't great an indicative that the treatment may not be working. He is meeting with a radiation oncologist next week for spot radiation to his ribs which are quite painful. He hot his Zometa infusion today which will probably cause more pain but I know it's necessary. She said there's a possibility the cancer could have infiltrated his bone marrow which is why his levels aren't improving and keep dipping back down.
What would his next step be? He did 9 rounds of taxodere already and it didn't seem to help at all, his psa went down to 9, but his disease progressed within a few months. I was really hoping he would get longer out of the xtandi 😞
I've been so positive and have done so much research to keep him positive but I've wobbled today. Dad has been swimming every second day last week, played 2 rounds of golf, he has been exhausted after so had a feeling his levels would be low but other than that I thought he was really coming on good.
Today will really have set him back, he is Captain of his Golf Club this year, he has so much he wants to do. He had to retire early because of this disease it breaks my heart to think he won't keep fighting.
Any help or advice is greatly appreciated. X
What next after chemo?
Advice needed please.
Off Xtandi, what next?
Failed Docetaxel, then Xtandi, what next?
Jevtana would be next, if his blood work is up to it. Biopsy a metastasis.
Thank u, is there a chance that will be of more help than the taxodere?
That's exactly what it was approved for.
Dad met with radiation oncologist yesterday, he didn't even need a scan to see dad has a large Tumour (met) on his rib, doing a long hard session of spot radiation tomorrow. He is confident that will relieve the pain and progression in the area.. I guess that means he will be taken off the trail as whether its a new on or progression of existing its still progression. Dad is OK now that he has answers but dissapointed that the disease is still progressing. I know he really doesn't want to do chemo again 😢 scans march 3rd & 9th then meeting consultant after that. The lovely radiation consultant explained to him the swelling in his lower legs was due to pressure on his heart and medication to treat the cancer.
It may help him to know that his rib pain may increase for 1-2 weeks after the radiation before it decreases. That's from the temporary inflammation. Anti-inflammatories may help.
Thank you 🤗