On April 10th with the consent of my MO, I began taking my 1000mg dose of Zytiga/Pred. with food. On average the meals ranged between 500 and 750 calories and 30 to 50 grams of fat. This was a last ditch effort to prolong the effectiveness of Zytiga as my PSA after falling from 32 to 12 began to rise back up, you can read my entire treatment history in my post titled, Viewer Discretion Advised.
Unfortunately combining Zytiga with food did nothing to stop the rise of my PSA, and after 35 days my PSA has risen to 33. Putting that disappointment aside I did not experience any physical side effects. Below I have listed my blood numbers, if anyone has any questions please do ask. BTW I do have Gilbert's syndrome so I'm not sure if that skews my numbers in regards to taking Zytiga with food. Best to all.
March 21 2019. (Prior to taking Zytiga/Food)
ALKALINE PHOSPHATASE 152
ALT 17
AST 15
BILIRUBIN, TOTAL 1.5
GLUCOSE 93
PSA 16.7
April 10 2019. (Prior to taking Zytiga/Food)
ALKALINE PHOSPHATASE 142
ALT 22
AST 23
BILIRUBIN, TOTAL 1.4
GLUCOSE 104
PSA 18.1
April 24 2019. (2 weeks into taking Zytiga/Food)
ALKALINE PHOSPHATASE 154
ALT 18
AST 19
BILIRUBIN, TOTAL 1.4
GLUCOSE 165
PSA 19.6
May 15 2019 (35 days taking Zytiga/Food)
ALKALINE PHOSPHATASE 145
ALT 13
AST 17
BILIRUBIN, TOTAL 1.1
GLUCOSE 112
PSA 33.4
As a note my MO is working on getting me into a trial of Olaparib, Cabazitaxel, Carboplatin, and Prednisone before moving on to a Lu 177-PSMA-617 trial.