Pembro + Insight PD-1 antibody trial - Advanced Prostate...

Advanced Prostate Cancer

20,967 members26,131 posts

Pembro + Insight PD-1 antibody trial

johngwilk profile image
4 Replies

Does anyone know anything about a trial in the design stage of pembrolizumab (Keytruda) + insight PD-1 antibody?

I have the CDK12 mutation, which we’re currently treating with taxotere + carbolplatin in clinical trial. I just had my 5th infusion. After 4 infusions, my PSA has dropped from 948 to 540. The goal is to keep me stable until the start of the pembro+ trial. I’d like to find more about the upcoming trial, including academic papers, but I’m not finding anything.

Thanks.

— John

Written by
johngwilk profile image
johngwilk
To view profiles and participate in discussions please or .
Read more about...
4 Replies
Tall_Allen profile image
Tall_Allen

For input on a different combination of checkpoint inhibitors:

healthunlocked.com/advanced...?

johngwilk profile image
johngwilk in reply to Tall_Allen

Very informative. Thanks.

j-o-h-n profile image
j-o-h-n

This might not apply to you. I've posted many many times that besides my Pca I am also fighting stage IV lung melanoma. Keytruda (15 sessions so far) has worked. I've been on a vacation off of Keytruda for more than 6 Months. Each treatment is $30k. Yep $30K. I have asked both my Pca Oncologist and my Melanoma Oncologist if I may be getting any benefit for my Pca using Keytruda. Both said NO but that was more than a year ago. Who knows now?

Good Luck, Good Health and Good Humor.

j-o-h-n Thursday 02/28/2019 6:40 PM EST

Michelle56pr profile image
Michelle56pr

did you participate in the trial?

You may also like...

Pembro and Olaparib clinical trial

ahead of it. Consult at Johns Hopkins offered Pembro and Olaparib combo clinical trial . I did not...

Cycle 1 of Clinical Trials

round of treatments for a new clinical trial that involves an infusion of a novel platinum based...

Question on stopping ADT - Keytruda/pembro

undetectable PSA for almost a year <0.01 then it slowly crept up to 0.19 over the second year. Last...

Ups and downs of screening for a Phase 1 trial

active. If he gets on a trial, all medication will have to be cleared with the trial team. Quite a...

Vision trial completion

my 6th and final infusion of lu-177 in the vision trial. It has worked for me (PSA was 375 at start,