MO told me that I was doing a tremendous job researching my PCa disease, but also suggested I get genetic testing by taking the Color saliva test. I did, and got the results several days ago. I am positive for the BRCA2 gene mutation.
As part of the Color program, which costs just $99 for the test, I was entitled to a call with a genetics counselor. I was told that having the mutation predisposes me to aggressive metastatic PC, which I was diagnosed with in June 2018. So I ask myself what if I had known then what I know now; should I have had the test years ago?. But, despite my family history of my father, mother and only sibling sister who all died of different cancers, I had been told that none were known to be hereditary. Now I need to tell my two daughters (age 34 and 38), and make sure they get tested. I feel horrible about this. It's bad enough that I am fighting cancer. Now my children will need to be very vigilant should they be tested positive, hopefully god forbid catching either breast or ovarian cancer early enough. While it is still better to know than not, it is devastating news!
Now I have continued to do research, and found that maybe using a PARP inhibitor could be helpful for me. Asked my oncologist (not the one that said I should consider the Color test) about the TRITON2 study, and Rucaparib. He told me that CINJ, where he works, was a participant in the trial. He understands that the study addressed castrate resistant patients, which I am not. I am on Eligard, Zytiga. Prednisone and Xgeva, which are working for me now with PSA down from 20 to 0.2 in 3 months. Also having robotic prostatectomy this Nov 14 as part of the SIMCAP clinical trial.
Should I consider adding Rucaparib at this point, or wait until I become castrate resistant??? Also, what about using other PARP inhibitors, if available, such as Lynparza, Olaparib, Nanotization or chemo carboplatin?
Any experience with PARP inhibitors (Niraparib)? 
Treatment after chemo - PARP inhibitor or immunotherapy trial?
