Starting a trial on Thursday.

[wrando]

I finally got into a trial. Have any of you seen this one or better yet are in the study?

A Phase 1 Study To Evaluate Escalating Doses Of A Vaccine-Based Immunotherapy Regimen For Prostate Cancer (PrCa VBIR)

NCT02616185

I've been stage four for 6 years psa around 100...no chemo, but Provenge, Casodex, and Zytiga.

Smilow Cancer center New Haven CT Dr. Petrylak

[pjoshea13]

clinicaltrials.gov/ct2/show...

clinicaltrials.gov/ct2/show...

-Patrick

[charmander]

Congrats on getting in!!! I'm currently researching clinical trials myself and saw this one. I believe this one excludes anyone who has had chemo. I'll post my trial when I get accepted. Good luck and keep us posted on your progress. How far do you have to travel to the Smilow Center.

Charlie

[wrando in reply to charmander]

Hi Charlie...Smilow is only an hour away...but trials require a lot of visits and testing. Keep you posted.

[j-o-h-n]

Good Job!

Good Luck and Good Health.

j-o-h-n Tuesday 03/06/2018 5:03 PM EST

[AlanMeyer]

Hello wrando,

Thank you for joining this trial. What you are doing will benefit a lot of people, not just you. I'm very hopeful about the future of immunotherapy and I think it's great that new drugs are coming out that advance the state of the art and that people like you are volunteering to be tested with them.

Looking at the trial documents using the link posted by Patrick, I see that some very big name universities and research hospitals are participating in this trial. I think that means that a bunch of top experts think this drug has promise. I think that bodes well for you. I hope you have a great response to the treatment.

Best of luck.

Alan

[wrando in reply to AlanMeyer]

Thanks Alan...a couple of the drugs are FDA approved for other cancers and there are parts to this trial I don't yet understand, but I guess I'll find out tomorrow.

[AlanMeyer in reply to wrando]

Please keep us up to date with your experience.

Thanks.

Alan

[wrando]

Sorry folks, but after two days of scans and every imaginal test I was turned down for the trial. I was in the office expected to start and they said sorry. It's the second time at Smilow. I'm sick of this shit and this life. They want guinea pigs or just ones that might sell them drugs. I'm finished...ride it out...get some morphine and when it get too bad just up the dose

[AlanMeyer in reply to wrando]

I understand your frustration. If you can afford going to Germany or Australia, or can get into one of the U.S. trials, it may still be worth trying the Lutetium-177 treatment. It's totally different from hormone or chemo therapies so failing those, as far as I know, will not mean that the Lu-177 won't work.

Whatever happens, it looks like you've got at least a little time left. I hope you can find some meaning and joy in that time by concentrating on making the best of it.

Some of us will die sooner than others and some will die of things other than prostate cancer, but we're all going to die. We can't live with the hope of cheating death. So we mustn't cheat ourselves of the life we have. Please don't despair. Take hold of life and make it as meaningful to you as you can.

I wish you the best.

Alan

[wrando]

Thanks Alan...I hear ya...I was just so frustrated because I was at the hospital to start the infusions and they said I was wanted upstairs...I knew it was over as this isn't my first rejection.

BTW I emailed the people in Texas about their Lu-177 trial...see what they say. I live in CT and would relocate for a while.

[Hidden in reply to wrando]

Texas is doing 177Lu-PSMA?

[wrando in reply to Hidden]

clinicaltrials.gov/ct2/show... it's here