Had my 6th and last Xofigo (radium 223) infusion yesterday, PSA .66. Recap, minimal side effects through all 6 injections. Great pain relief by 2 weeks after 2nd injection allowing me to go off Hydromorphone 2mg every 4 hours. Pain now managed well with naproxen sodium 220 mg every 8 hours, keeps pain tolerable at 2-3 level. Oncologist says reasonable to expect pain relief to continue for another 6-9 months depending on aggressiveness of cancer and development of new metastasis. Hope this is helpful to anyone considering Xofigo.