Hi there, I've been feeling awfully tired and irritable lately (my poor boyfriend) and experienced unexplained weight loss. My blood tests came back with a TSH level of 27 and I think a T4 level of 9.2 (I'm not sure what kind of T4 this was looking at ie free). I was also positive for an anti-thyroid antibody although I don't know which one. The doctor has given me a daily 50mg dose of Levothyroxine tablets to start with and I'm really hoping for some results with this. My only concern is the strange weight loss, surely I should have been gaining weight with an underactive thyroid? Does anyone have an explanation for this? I'd appreciate any comments/advice.