Hi
I have been told that I have autoimmune thyroid dysfunction and currently seeing an endocrinologist regarding this.I have just finished course of strong vitamin D tablets and due to have a variety of tests this week including cortisol level ,coeliac screening ,T-shirt T4 T3and antibodies .My question is can thyroid problems cause HBA1C levels to rise ?
I am aware of problems with cholesterol/triglycerides,are there any other things that it could potentially affect ?
Yes HBA1C often increases when hypothyroid and levels should reduce once your hypothyroidism is correctly treated
medical.advancedresearchpub...
Low folate or iron both very common when hypothyroid, can also increase HBA1c
bmcendocrdisord.biomedcentr...
What are your most recent TSH, Ft4 and Ft3 thyroid results
And have you had ferritin levels tested yet
vitamin D
Vitamin D levels need retesting at end of loading course and you will need to take ongoing daily vitamin D supplements
Test twice yearly when supplementing
Can test via NHS private testing service
GP will often only prescribe to bring vitamin D levels to 50nmol.
Some areas will prescribe to bring levels to 75nmol or even 80nmol
leedsformulary.nhs.uk/docs/...
GP should advise on self supplementing if over 50nmol, but under 75nmol (but they rarely do)
mm.wirral.nhs.uk/document_u...
But, improving to around 80nmol or 100nmol by self supplementing may be better
pubmed.ncbi.nlm.nih.gov/218...
vitamindsociety.org/pdf/Vit...
Vitamin D mouth spray by Better You is very effective as it avoids poor gut function.
There’s a version made that also contains vitamin K2 Mk7.
One spray = 1000iu
amazon.co.uk/BetterYou-Dlux...
It’s trial and error what dose we need, with thyroid issues we frequently need higher dose than average
NHS Guidelines on dose vitamin D required
panmerseyapc.nhs.uk/media/2...
Web links about taking important cofactors - magnesium and Vit K2-MK7
Magnesium best taken in the afternoon or evening, but must be four hours away from levothyroxine
betterbones.com/bone-nutrit...
medicalnewstoday.com/articl...
livescience.com/61866-magne...
sciencedaily.com/releases/2...
Vitamin K2 mk7
Yes, glucose levels and ultimately HbA1c (which is a measure of your glucose concentration over a period of 2-3 months) can very much be impacted by thyroid hormones.
In your last post, you have mentioned that you took 150mcg levothyroxine before your thyroid function test - this could have influenced your T4 reading, which was slightly over the range and your TSH was very low, giving you a false high reading for the T4 (peak plasma concentrations of T4 are reached between 2-3h after ingestion).
I believe that due to your last result, your GP/endo has reduced your medication, therefore you had less thyroid hormones available. T3 is the active hormone and heavily involved in glucose metabolism, lipid metabolism and other important metabolic processes, so if your T3 levels were lower, this could have impacted your control of these metabolic functions.
So in short, yes, thyroid hormones can have an impact on glucose levels, therefore it is important to keep them in an optimal range, especially the T3.
now to alternate levothyroxine to 125 one day 150 the next.He will review me in April 2025.
Bloods should be retested 8-10 weeks after dose reduction
Are you cutting Accord 50mcg in half to get 25mcg
Ferritin levels need testing too
No not using accord at the moment it is teva for the 25 mcg. I am having coeliac ,cortisol,Vit D ,T-SH T4 T3 plus antibodies.Also done to do renal vit B12 and ferritin in 3days time.
Accord only make 50mcg and 100mcg tablets.
Accord is also boxed as Almus via Boots, and as Hillcross
Teva brand upsets many people
Have you noticed any issues since starting on Teva
Many people find Levothyroxine brands are not interchangeable.
Lactose free brands - currently Vencamil or Teva
Vencamil is lactose free and mannitol free. originally only available as 100mcg only, but 25mcg, 50mcg and 75mcg tablets became available Sept 2024
Prior to March 2023 Vencamil was called Aristo
Vencamil often very well tolerated/best option for many people
How to get Vencamil stocked at your local pharmacy
healthunlocked.com/thyroidu...
Posts discussing Vencamil
healthunlocked.com/thyroidu...
healthunlocked.com/thyroidu....
Teva makes 12.5mcg 25mcg, 50mcg, 75mcg and 100mcg
Many patients do NOT get on well with Teva brand of Levothyroxine.
Teva is lactose free, but contains mannitol as a filler instead of lactose, which seems to be possible cause of problems. Mannitol seems to upset many people, it changes gut biome
Helpful post about Teva
healthunlocked.com/thyroidu...
Posts that mention Teva
healthunlocked.com/search/p...
Teva poll
healthunlocked.com/thyroidu...
Relatively new ……Hillcross brand
This is a box, rather than a brand. 50mcg and 100mcg are Accord brand….but beware 25mcg is Teva brand
Mercury Pharma make 25mcg, 50mcg and 100mcg tablets
Mercury Pharma also boxed as Eltroxin. Both often listed by company name on pharmacy database - Advanz
Wockhardt is very well tolerated, but only available in 25mcg tablets. Some people remain on Wockhardt, taking their daily dose as a number of tablets
July 2024 Crescent levothyroxine. Dosages: 12.5, 25, 50, 75, 100
(Not yet known if all approved dosages are or will be available).
Helpful post about different brands
healthunlocked.com/thyroidu...
List of different brands available in U.K.
thyroiduk.org/if-you-are-hy...
Once you find a brand that suits you, best to make sure to only get that one at each prescription.
Watch out for brand change when dose is increased or at repeat prescription.
Government guidelines for GP in support of patients if you find it difficult/impossible to change brands
gov.uk/drug-safety-update/l...
If a patient reports persistent symptoms when switching between different levothyroxine tablet formulations, consider consistently prescribing a specific product known to be well tolerated by the patient.
academic.oup.com/jcem/artic...
Physicians should: 1) alert patients that preparations may be switched at the pharmacy; 2) encourage patients to ask to remain on the same preparation at every pharmacy refill; and 3) make sure patients understand the need to have their TSH retested and the potential for dosing readjusted every time their LT4 preparation is switched (18).
And here
pharmacymagazine.co.uk/clin...
Discussed here too
healthunlocked.com/thyroidu...
Thanks for that info .I am having a lot of stomach/bowel issues but need to rule out coeliac first but it could be down to teva .I need to do this one step at a time ruling things out until I can hopefully be at optimal levels of everyone and then hopefully I will start to feel better.
So ditch the Teva and start cutting Accord tablets in half to get 25mcg - use a sharp craft scalpel
Mop up any crumbs with damp finger
Store remaining half in weekly pill dispenser
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