Interpreting results : Hi allI don't usually post... - Thyroid UK

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Interpreting results

Vicky567 profile image
25 Replies

Hi allI don't usually post here. And I'm not an expert with Thyroid results one bit.

I had a medichecks thyroid blood test done last Thursday.

The GP writes at the top about what the think/recommend about your results

So- my free thyroxine was 11.8 and my TSH was,1.26.

She wrote that this is at a healthy stage but if the free thyroxine goes lower especially if the TSH goes higher next blood test then I could have underactive thyroid.

What do you guys think to the results here?

I'm worried....she did say it could be transient and could go back higher on iys own (the free T). What should I do?

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Vicky567 profile image
Vicky567
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25 Replies
TiggerMe profile image
TiggerMeAmbassador

Do you have the fT3 result?

Also did the test include any antibodies testing?

Vicky567 profile image
Vicky567 in reply toTiggerMe

Ji no it didn't test T3....but I've bought another kit by medichecks which includes T3.

Buddy195 profile image
Buddy195Administrator

can you take a screen shot of the test results (ensuring no name visible) and add to your post. You can do this by replying to yourself and clicking in the ‘photo’ icon below to add an image.

Vicky567 profile image
Vicky567 in reply toBuddy195

Couldn't upload pic

Vicky567 profile image
Vicky567 in reply toBuddy195

Buddy my pic is below of results

SlowDragon profile image
SlowDragonAmbassador

Presumably Ft4 is below range

Are you on any replacement thyroid hormones and/or diagnosed as hypothyroid

Was test done early morning, ideally just before 9am, only drink water between waking and test and (if on Levo ….last dose levothyroxine 24 hours before test )

This gives highest TSH, lowest FT4 and most consistent results. (Patient to patient tip)

Extremely important to also test vitamin D, folate, B12 and ferritin

Were these tested?

Vicky567 profile image
Vicky567 in reply toSlowDragon

Yes all others testes all normal.Haven't been diagnosed as she said to repeat test in 3 months but I'm not waiting that long

SlowDragon profile image
SlowDragonAmbassador in reply toVicky567

Please add vitamin results and ranges

Normal is not necessarily optimal

What’s the Ft3 result and thyroid antibodies results

SlowDragon profile image
SlowDragonAmbassador in reply toVicky567

Your TSH is low and with below range (just) of Ft4

TSH should rise with low Ft4

Obviously need to see other test results as these can affect things

Vicky567 profile image
Vicky567 in reply toSlowDragon

So you think this could go back up to normal by itself?

Vicky567 profile image
Vicky567 in reply toSlowDragon

I'm actually just going off to collect my results print out for all those tests you've just mentioned. Il let you know soon

Vicky567 profile image
Vicky567 in reply toSlowDragon

Slow dragon here are my vitamins -

Vitamin D- 87 (50.00-200.oonmol/L

Serum folate- 4.9 (3.00- 20.50ug/L

Serum ferritin - 138 (30.00- 250.00ug/L

Vitamin B12 - 224 (200.00- 900.00ng/L

Serum iron level - 17 (9.00- 30.00umol/L

Serum transferritin- 3.44 (1.80- 3.82g/L

Transferritin saturation index - 19 (15.00- 50.00%

SlowDragon profile image
SlowDragonAmbassador in reply toVicky567

So B12 and folate are both extremely low

Are you vegetarian or vegan?

Are you taking any medications that lower B12

Eg Metformin or any PPI

If you aren’t

Request GP test for Pernicious Anaemia

you may need B12 injections

If GP doesn’t prescribe B12 injections you will definitely need daily B12 supplements

Low B12 symptoms

b12deficiency.info/signs-an...

methyl-life.com/blogs/defic...

NICE guidelines on B12 and testing

healthunlocked.com/redirect...

With serum B12 result below 500, (Or active B12 below 70) recommended to be taking a separate B12 supplement

A week later add a separate vitamin B Complex 

Then once your serum B12 is over 500 (or Active B12 level has reached 70), you may be able to reduce then stop the B12 and just carry on with the B Complex.

If Vegetarian or vegan likely to need ongoing separate B12 few times a week

Highly effective B12 drops

natureprovides.com/products...

Or

B12 sublingual lozenges

uk.iherb.com/pr/jarrow-form...

cytoplan.co.uk/shop-by-prod...

In-depth article on different forms of B12

perniciousanemia.org/b12/fo...

B12 range in U.K. is too wide

Interesting that in this research B12 below 400 is considered inadequate

healthunlocked.com/thyroidu...

perniciousanemia.org/b12/le...

And why aiming to keep B12 over 500 recommended

perniciousanemia.org/b12/le...

Great reply by @humanbean on B12 here

healthunlocked.com/thyroidu...

Low folate

supplementing a good quality daily vitamin B complex, one with folate in (not folic acid)

This can help keep all B vitamins in balance and will help improve B12 levels too

Difference between folate and folic acid

healthline.com/nutrition/fo...

B vitamins best taken after breakfast

Igennus B complex popular option. Nice small tablets. Most people only find they need one per day. But a few people find it’s not high enough dose and may need 2 per day and/or may need separate methyl folate couple times a week

Post discussing different B complex

healthunlocked.com/thyroidu...

Thorne Basic B recommended vitamin B complex that contains folate, but they are large capsules. (You can tip powder out if can’t swallow capsule) Thorne can be difficult to find at reasonable price, should be around £20-£25. iherb.com often have in stock. Or try ebay

IMPORTANT......If you are taking vitamin B complex, or any supplements containing biotin, remember to stop these 5-6 days before ALL BLOOD TESTS , as biotin can falsely affect test results

endocrinenews.endocrine.org...

In week before blood test, when you stop vitamin B complex, you might want to consider taking a separate folate supplement (eg Jarrow methyl folate 400mcg) and continue separate B12 if last test result serum B12 was below 500 or active B12 (private test) under 70

SlowDragon profile image
SlowDragonAmbassador in reply toVicky567

was CRP tested (inflammation)

Please add results

Ferritin looks reasonable, but can be falsely high if you have high inflammation

Will tag humanbean and FallingInReverse to comment on iron and ferritin

SlowDragon profile image
SlowDragonAmbassador in reply toVicky567

Retest thyroid levels 2-3 months after working on improving low vitamin levels

Vicky567 profile image
Vicky567

Above are my results

Thyroid results
Vicky567 profile image
Vicky567

Above are my results

Thyroid results
DippyDame profile image
DippyDame

So your GP thinks FT4 of 11.8(12 - 24) is a healthy result.

Afraid not! It's below the reference range.

Your GP is only looking at TSH I think, and I'm not convinced her thyroid knowledge is robust.

TSH of 1.6 may look reasonable but you need labs for both Frees to check your T4 to T3 conversion status amongst other things

Was test done at 9am to achieve highest TSH?

Did you test well away from any food or drinks which could skew absorption/ results

If so FT4 is far to low and you are hypothyroid and in need of replacement hormone

However a test to include the following, taken under advised conditions will give a clearer picture....

TSH, FT4, FT3, vit D, vit B12, folate, ferritin ....and thyroid antibodies TPO and Tg if not already tested

.she did say it could be transient and could go back higher on iys own (the free T).

An odd comment

What should I do?

Do nothing until you have had a full thyroid test as above

Post the results for advice

Vicky567 profile image
Vicky567 in reply toDippyDame

Hi hun thanks I'm very new to all this. I've just collected my vitamin results and have written them out for a user above called slow dragon if u want to take a look?

Vicky567 profile image
Vicky567 in reply toDippyDame

Do u think it's best I go to an Endocrinologist?

DippyDame profile image
DippyDame in reply toVicky567

Not before you have a clearer picture of what is going on, which a full test will do.

Don't worry it looks like you may just need to start on replacement hormone which your GP can do.

Members will guide you on the way forward

Nutrients

Your results underlined....you need to work on some results

Vitamin D- 87 (50.00-200 nmol/L

The Vit D Council, the Vit D Society and Grassroots Health all recommend a level of 100-150nmol/L (40-60ng/ml), with a recent blog post on Grassroots Health mentioning a study which recommends over 125nmol/L (50ng/ml).

Serum folate- 4.9 (3.00- 20.50ug/L

Folate is recommended to be at least half way through range

Serum ferritin - 138 (30.00- 250.00ug/L

Optimal ferritin level for thyroid function is 90-110ug/L

Vitamin B12 - 224 (200.00- 900.00ng/L

According to an extract from the book, "Could it be B12?" by Sally M. Pacholok:

We believe that the 'normal' serum B12 threshold needs to be raised from 200 pg/ml to at least 450 pg/ml because deficiencies begin to appear in the cerebrospinal fluid below 550".

"For brain and nervous system health and prevention of disease in older adults, serum B12 levels should be maintained near or above 1000 pg/ml."

Serum iron level - 17 (9.00- 30.00umol/L

Serum transferritin- 3.44 (1.80- 3.82g/L

Low levels are present in iron overload, high levels in iron deficiency. Should be interpreted in conjunction with other components of iron studies.

Transferritin saturation index - 19 (15.00- 50.00%

Transferrin saturations of less than 20% indicate iron deficiency, while transferrin saturations of more than 50% suggest iron overload

Vicky567 profile image
Vicky567 in reply toDippyDame

Awww I'm really worried now as I'm already going through a withdrawal from an antidepressant. It's so tough

SlowDragon profile image
SlowDragonAmbassador in reply toVicky567

If you get B12 and folate levels too good levels this may likely to help with depression

mayoclinic.org/diseases-con....

GP should have tested all vitamin levels before starting antidepressants…….but that almost never happens

DippyDame profile image
DippyDame in reply toVicky567

Hang on in there, it is tough but you can do this.

Many years ago I was put on a low dose of Sertraline for pain, after I was diagnosed with Fibromyalgia. I had no idea what it involved until I decided to stop it. I did it very slowly and it was fine.

No need to worry....easy to say with hindsight....but you will be ok.

We're all here to help.

tattybogle profile image
tattybogle

the reason for the 3 month wait to retest thyroid levels , is because there can be other temporary reasons for out of range thyroid results., such as non thyroidal illness, and several others .

it would be irresponsible of GP/ or endo to start anyone on levothyroxine for life without first confirming that the person really is hypothyroid and it's not just a passing unrelated issue causing the out of range results , and this takes time because thyroid hormone levels can be relatively slow to change ..... so they can't just test again in a week as that wouldn't rule out a temporary cause .

3 months is arguably too long , maybe 6-8 weeks would be kinder to patients , and some GP may be willing to shorten the timescale a little , depending on symptoms / any other factors going on...... but any shorter than that is just too soon to be useful.

the guidelines NHS GP's have to follow do not let them start someone on levo just for one slightly out of range fT4 result for good reasons.

if the repeat test again shows below range fT4 and TSH is still within range as it is now , then the GP would need to refer you to endocrinology (GP's can't usually prescribe levo unless / until TSH is out of range) .

because if your TSH is still within range that would suggest Secondary / Central Hypothyroidism... not primary hypothyroidism, and GP's cannot start treatment for secondary hypo,,, it needs to be properly diagnosed by an endo, because it involves testing other pituitary hormones to determine the cause . It is difficult to get diagnosed with secondary hypo, as they believe its rare.

"primary hypothyroidism "is where the thyroid gland itself isn't working properly ...

"secondary / central hypothyroidism" is where the thyroid itself is ok , but the pituitary / hypothalamus is not telling the thyroid to work.

cks.nice.org.uk/topics/hypo... this info does cover secondary hypo ,

nice.org.uk/guidance/ng145 This guideline covers investigating all suspected thyroid disease and managing primary thyroid disease (related to the thyroid rather than the pituitary gland). this one mainly covers primary hypo ( where TSH is high), and only mentions secondary in the sense of 'refer to endocrinology if pituitary disease is suspected '

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